Medicinal Chemistry—III - 1st Edition - ISBN: 9780408705387, 9781483284743

Medicinal Chemistry—III

1st Edition

Main Lectures Presented at the Third International Symposium on Medicinal Chemistry

Editors: P. Pratesi
eBook ISBN: 9781483284743
Imprint: Butterworth-Heinemann
Published Date: 1st January 1973
Page Count: 176
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Medicinal Chemistry–III provides information pertinent to the fundamental aspects of medicinal chemistry. This book discusses the mechanism of action of drugs at the molecular level. Organized into eight chapters, this book begins with an overview of the systems for protein biosynthesis that are classified according to their mechanism and the selective action of drugs on their reactions. This text then examines the key structure in the biosynthesis of the peptidoglycans of bacterial cell walls. Other chapters consider the enzymes that transcribe DNA synthesizing RNA, which have structural differences in eukaryotic and prokaryotic cells. This book discusses as well the concepts for drug screening as they have been emerged from neurochemical research. The final chapter deals with the significance of molecular orbital theory in the hands of the biologist or chemists, which lies in its ability to derive information regarding the properties of molecules. This book is a valuable resource for organic, physical, and biological chemists.

Table of Contents


Opening Remarks

The Mechanisms of Selectivity and Action of Protein Synthesis Inhibitors

The Significance of D-Alanyl-D-Alanine Termini in the Biosynthesis of Bacterial Cell Walls and the Action of Penicillin, Vancomycin and Ristocetin

Inhibitors of the Transcribing Enzymes

Analogues of Cyclic Amp and Their Physiological Response

Principles of Neurochemistry and Drug Screening Procedures in Neuropsychopharmacology

Active Polypeptides of the Amphibian Skin and Their Synthetic Analogues

Some Biological Applications of Regular Solution Theory

The Prediction of Molecular Conformation As A Biologically Significant Property

Concluding Remarks


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© Butterworth-Heinemann 1973
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About the Editor

P. Pratesi

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