Medicinal Chemistry—III

Medicinal Chemistry—III

Main Lectures Presented at the Third International Symposium on Medicinal Chemistry

1st Edition - January 1, 1973

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  • Editor: P. Pratesi
  • eBook ISBN: 9781483284743

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Medicinal Chemistry–III provides information pertinent to the fundamental aspects of medicinal chemistry. This book discusses the mechanism of action of drugs at the molecular level. Organized into eight chapters, this book begins with an overview of the systems for protein biosynthesis that are classified according to their mechanism and the selective action of drugs on their reactions. This text then examines the key structure in the biosynthesis of the peptidoglycans of bacterial cell walls. Other chapters consider the enzymes that transcribe DNA synthesizing RNA, which have structural differences in eukaryotic and prokaryotic cells. This book discusses as well the concepts for drug screening as they have been emerged from neurochemical research. The final chapter deals with the significance of molecular orbital theory in the hands of the biologist or chemists, which lies in its ability to derive information regarding the properties of molecules. This book is a valuable resource for organic, physical, and biological chemists.

Table of Contents

  • Contents

    Opening Remarks

    The Mechanisms of Selectivity and Action of Protein Synthesis Inhibitors

    The Significance of D-Alanyl-D-Alanine Termini in the Biosynthesis of Bacterial Cell Walls and the Action of Penicillin, Vancomycin and Ristocetin

    Inhibitors of the Transcribing Enzymes

    Analogues of Cyclic Amp and Their Physiological Response

    Principles of Neurochemistry and Drug Screening Procedures in Neuropsychopharmacology

    Active Polypeptides of the Amphibian Skin and Their Synthetic Analogues

    Some Biological Applications of Regular Solution Theory

    The Prediction of Molecular Conformation As A Biologically Significant Property

    Concluding Remarks

Product details

  • No. of pages: 176
  • Language: English
  • Copyright: © Butterworth-Heinemann 1973
  • Published: January 1, 1973
  • Imprint: Butterworth-Heinemann
  • eBook ISBN: 9781483284743

About the Editor

P. Pratesi

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