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Medical Epigenetics - 2nd Edition - ISBN: 9780128239285

Medical Epigenetics, Volume 29

2nd Edition

Series Volume Editor: Trygve Tollefsbol
Paperback ISBN: 9780128239285
Imprint: Academic Press
Published Date: 30th August 2021
Page Count: 976
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Table of Contents

Section I: Overview
1. Advances in Medical Epigenetics

Section II: Basic Principles of Epigenetics
2. DNA Methylation: Basic Principles
3. Histone-deacetylases Principles in Epigenetics
4. Basics of Noncoding RNAs in Epigenetics

Section III: General Medical Aspects of Epigenetics
5. Epidemiological Epigenetics in Medicine
6. Lifestyle and Preventive Medical Epigenetics
7. Environmental Medical Epigenetics
8. Behavioral Medical Epigenetics
9. Medical Epigenetics in Twins
10. Epigenetic Biomarkers of Disease
11. Prognostic Epigenetics

Section IV: Epigenetics of System Disorders
12. Immune System Disorders and Epigenetics
13. Pulmonary Diseases and Epigenetics
14. Cardiovascular Disorders and Epigenetics
15. Epigenomics of Intestinal Disease
16. Epigenetics of Skin Disorders
17. Epigenetics in Bone and Joint Disorders
18. Epigenetics of Muscle Disorders
19. Epigenetics of Psychiatric Disorders
20. Reproductive Disease Epigenetics
21. Epigenetics in Ocular Medicine

Section V: Multi-system Medical Epigenetics
22. Pediatric Diseases and Epigenetics
23. Epigenetics of Infectious Diseases
24. Clinical Utility of Solid Tumor Epigenetics
25. Epigenetics in Acute Myeloid Leukemia
26. Skin Cancer Epigenetics
27. Epigenetic Regulation in Cancer Metastasis
28. Epigenetics in Exercise Science and Sports Medicine

Section VI: Bioinformatics of Epigenetic Medicine
29. Network Analysis in Medical Epigenetics
30. Machine Learning in Epigenetic Diseases

Section VII: Pharmacology of Epigenetics
31. Toxicology and Epigenetics
32. Pharmacoepigenomics

Section VIII: Therapeutic Epigenetics
33. Therapeutics and DNA Methylation Inhibitors
34. Histone Deacetylase Inhibitors in Medical Therapeutics
35. NAD+-dependent Deacetylases and Medical Therapy
36. Experimental Approaches Towards Histone Acetyltransferase Inhibitors as Therapeutics
37. Histone Methylation Modifiers in Medical Therapeutics
38. Therapeutics of Epigenetic-based RNA molecules
39. Natural Epigenetic-modifying Molecules in Medical Therapy
40. Combining Epigenetic Drugs with Other Treatments in the Clinic
41. Epigenetics of Pain Management
42. Precision Medical Epigenetics
43. Epigenetics and Regenerative Medicine
44. Stem Cell Epigenetics in Medical Therapy
45. Clinical Trials of Epigenetics Drugs

Section IX: Medical Epigenetics: Future Prospects
46. Prospective Advances in Medical Epigenetics


Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine.

This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs.

Key Features

  • Features chapters from leading researchers and clinicians dedicated to the burgeoning role of epigenetics in medical practice
  • Covers emerging topics, including twin epigenetics, as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine
  • Organized from system disorders to multi-system disorders that involve epigenetic aberrations
  • Examines the role of epigenetics in precision medicine


Human geneticists; human genomicists; translational researchers in genomic medicine, epigenetics, biochemistry, molecular biology; life science researchers; developmental biologists. Clinicians and graduate students in the biosciences


No. of pages:
© Academic Press 2021
30th August 2021
Academic Press
Paperback ISBN:

Ratings and Reviews

About the Series Volume Editor

Trygve Tollefsbol

Trygve Tollefsbol is a Professor of Biology and a Senior Scientist in the Comprehensive Center for Healthy Aging, the Comprehensive Cancer Center, the Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999. Dr. Tollefsbol has doctorate degrees in molecular biology and osteopathic medicine and has edited and co-authored numerous books on the topics of epigenetics, cancer and aging and is Series Editor of Translational Epigenetics. Dr. Tollefsbol is a Professor of Biology and a Senior Scientist in the Center for Aging, Comprehensive Cancer Center, Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999 and a Steering Committee Member of the UAB Center for Aging.

Affiliations and Expertise

Professor of Biology, Senior Scientist, Comprehensive Cancer Center, Comprehensive Center for Healthy Aging, University of Alabama at Birmingham, AL, USA