
Mechanobiology
From Molecular Sensing to Disease
Description
Key Features
- Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli
- Provides a review of diseases with known or purported mechanobiological underpinnings
- Includes the role of mechanobiology in tissue engineering and regenerative medicine
- Covers experimental methods to capture mechanobiological phenomena
Readership
Table of Contents
Section 1: Mechanobiological basis of diseases
1.1 Osteoporosis
1.2 Cardiovascular mechanics and disease
1.3 Glaucoma and eye diseases
1.4 Growth and development
1.5 Tissue engineering and regenerative medicineSection 2: Cellular basis of Mechanobiology
2.1 Cells as strain gages and load cells
2.2 Cell – extracellular matrix interactions
2.3 Mechanobiological pathways
2.4 Mechanically mediated epigeneticsSection 3: Experimental methods
3.1 Effects of shear stress on cells
3.2 Three-dimensional culture systems
3.3 Bioreactors
3.4 Tissue and organ on a chip systemsSection 4: Computational simulations in mechanobiology
4.1 Cell aggregation
4.2 Growth models
5. Future prospects and challenges
6. Bibliography
7. Glossary
Product details
- No. of pages: 254
- Language: English
- Copyright: © Elsevier 2019
- Published: December 1, 2019
- Imprint: Elsevier
- eBook ISBN: 9780128179321
- Paperback ISBN: 9780128179314