Mechanobiology in Health and Disease - 1st Edition - ISBN: 9780128129524

Mechanobiology in Health and Disease

1st Edition

Editors: Stefaan Verbruggen
Paperback ISBN: 9780128129524
Imprint: Academic Press
Published Date: 1st June 2018
Page Count: 650
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Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer.

A discussion of future perspectives for research completes the volume. This is a timely resource for both early-career and established researchers working on mechanobiology.

Key Features

  • Provides an essential digest of primary research from many fields and disciplines in one convenient volume
  • Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives
  • Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science


Early-career researchers in fields of bioengineering and biomedical engineering. Established researchers entering field of mechanobiology from fields of engineering, biology, biomechanics, tissue engineering, and related fields

Table of Contents

1. Techniques for Studying Mechanobiology

2. Cell Nuclear Mechanobiology and Pathogenesis

3. Mechanobiology During Development

4. Vascular Mechanobiology

5. Tendon Mechanobiology

6. Cartilage Mechanobiology

7. Neuromechanobiology

8. Mechanosensory Signals from the Gut in Health and Disease

9. Mechanobiology of eye and its role in diseases

10. Mechanobiology of the Primary Cilia in the Renovascular System

11. Bone Mechanobiology in Health and Disease

12. Heart Valve Interstitial Cell Mechanobiology

13. Mechanobiology of Metastatic Cancer

14. Mechanobiology of Skin Diseases and Wound Healing

15. Platelet Mechanoreception and Thrombosis


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© Academic Press 2018
Academic Press
Paperback ISBN:

About the Editor

Stefaan Verbruggen

Dr. Stefaan Verbruggen joined the Department of Bioengineering in 2014 as a postdoctoral Research Associate. Dr. Verbruggen’s research is in the area of developmental biomechanics, focusing on how the prenatal biomechanical environment affects the development of musculoskeletal diseases in later life. This research is funded by Arthritis Research UK. Prior to joining the Developmental Biomechanics Lab at Imperial College, Dr. Verbruggen conducted postdoctoral research in the Biomechanics Research Centre at the National University of Ireland Galway. Dr. Verbruggen holds a bachelor degree and a PhD in Biomedical Engineering from the National University of Ireland Galway, where his research focused on the mechanobiology of bone cells in both health and disease.

Affiliations and Expertise

Research Associate, Imperial College London, UK

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