Mechanisms of Morphogenesis

2nd Edition

Print ISBN: 9780123910622
eBook ISBN: 9780124157576
Imprint: Academic Press
Published Date: 17th April 2013
Page Count: 414
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Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form, Mechanisms of Morphogenesis, second edition is a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi.

By combining hard data with computer modeling, Mechanisms of Morphogenesis, second edition equips readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic program is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future

Table of Contents



A Note on References

SECTION I: Introductory Section

Chapter 1. Introduction: The Aims and Structure of This Book

Reference List

Chapter 2. Key Principles of Morphogenesis

The Idea of ‘Mechanism’


Emergence, Trap-Door Processes and the Dangers of Post-Hoc Reasoning

Feedback, Self-Assembly and Adaptive Self-Organization

Reference List

Chapter 3. The Power and Limitations of Self-Assembly

Introduction to Self-Assembly

Self-Assembly of Bilayered Membranes

One-Dimensional Self-Assembly: Actin

One-Dimensional Self-Assembly: Collagen

Three-Dimensional Self-Assembly: Simple Viruses

Quality Control in Self-Assembling Structures

Limitations to Self-Assembly

Reference List

SECTION II: Cell Shape and Cell Morphogenesis

Chapter 4. Morphogenesis of Individual Cells: A Brief Overview

Flattening and Elongation of Cells

Production of Cell Processes

Cell Fusions

Cell Cavitation

Changes in Cell Shape can Directly Drive Morphogenesis of Tissues

Reference List

Chapter 5. Animal Cell Shape: The Importance of the Cytoskeleton


Building and Placement of Tensile Microfilaments

Adaptive Self-Organization of the Microfilament Tension System

Assembly of the Microtubule System

Formation of Special Structures: Actin-Based Cell Protrusions

Reference List

Chapter 6. Cellular Morphogenesis in Plants

Diffuse Cell Elongation in Plants

Focused Cell Growth: Root Hairs, Pollen Tubes and Trichomes

Reference List

SECTION III: Cell Migration

Chapter 7. Cell Migration in Development: A Brief Overview

Morphogenesis by Coalescence of Dispersed Cells

Translocation of Groups of Cells from One Place to Anot


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© Academic Press 2013
Academic Press
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