1. Overview of Cardiovascular Aging (V. Somers). 2. Lipoprotein Metabolism and Molecular Pathogenesis of Atherosclerosis (N. Sakai). 3. Cytokines and the Pathogenesis of Atherosclerosis (G. Krishnaswamy). 4. Endothelium-Mediated Signaling and Vascular Aging (T. Luscher). 5. Nitric Oxide, Gender and Hypertension (S. Taddei). 6. Alterations of Ion Channels in Vascular Muscle Cells and Endothelial Cells during Hypertension and Aging (Y. Ohya). 7. Extracellular Matrix Changes and Vascular Smooth Muscle Signaling (E. Wilson). 8. Mitochondrial Electron Transport and Aging in the Heart (C.L. Hoppel). 9. Superoxide, Superoxide Dismutases and Cardiovascular Dysfunction (D. St. Clair). 10. Aging and the Red Cell (J. Rifkind). 11. Hyperhomocysteinemia and Cardiovascular Aging (M. Cattaneo). 12. Interactions of Selenium, Vitamin E, and Vitamin C in Atherosclerosis (J. May). 13. Dietary Antioxidants and Cardiovascular Disease (T. Hagen). 14. Extension of Cardiovascular Healthspan by Dietary Restriction: Molecular Mechanisms (M.P. Mattson).