Mechanisms in Radiobiology

Multicellular Organisms

1st Edition - January 1, 1960
Editors: Maurice Errera, Arne Forssberg
Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 2 - 6 6 3 2 - 9

Mechanisms in Radiobiology, Volume II: Multicellular Organisms presents the development of radiobiology, which has run parallel with the advancement of biology. This book discusses… Read more

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Mechanisms in Radiobiology, Volume II: Multicellular Organisms presents the development of radiobiology, which has run parallel with the advancement of biology. This book discusses the fundamental aspects of radiobiology in connection with the therapeutic use of X-rays in medicine. Organized into five chapters, this book begins with an overview of radiation effects on embryonic and adult organisms, particularly in mammals. This text then discusses the immunological processes in irradiated organisms. Other chapters consider the mechanisms of action of protective and sensitizing agents and examine the primary or secondary effects of the irradiation on the various organs. This book discusses as well the experimental possibilities of improving the recovery of irradiated mammals. The final chapter deals with the reactions of living organisms after a damaging dose of ionizing radiation, which is determined by a variety of biological and physical factors. This book is a valuable resource for radiobiologists, pathologists, scientists, physicists, clinicians, and research workers.

Contributors to Volume II Contributors to Volume I Preface Abbreviations and Units Contents of Volume I 1. General Biology: Gametes, the Developing Embryo, and Cellular Differentiation I. Effects of Ionizing Radiations on the Testes and Spermatozoa II. Effects of Ionizing Radiations on the Ovary and Ova III. Effects of Ionizing Radiations on the Embryo and/or the Fetus IV. References2. General Biology: The Adult Organism I. Introduction II. Blood-Forming Organs, Blood, and Lymphatic and Reticuloendothelial Systems III. Gonads IV. Endocrine Organs V. Skin and Epidermal Derivatives VI. Nervous System VII. Sense Organs VIII. Respiratory Tract IX. Circulatory System X. Alimentary Organs XL Urinary Tract XII. Bone and Cartilage XIII. Muscular and Connective Tissues XIV. Shortening of Life Span by Irradiation XV. References 3. Immunology I. Introduction II. Enhancement of Immunity by Radiation III. Inhibitory Effects of Radiation IV. Long-Term Changes in the Immunological Reactivity of the Irradiated Organism V. References4. Mechanisms of Protective and Sensitizing Action I. Introduction II. General Aspects of Protective and Sensitizing Action III. The Interaction of Protective and Sensitizing Agents with Radiation-Induced Free Radicals IV. Modification of Radiosensitivity by Interference with Radiolysis V. Modification of Radiosensitivity by Interaction with Activated Target Molecules VI. Modification of Radiosensitivity by Pharmacological Action VII. Modification of Radiosensitivity by Physicochemical and Chemical Alterations of Target Molecules VIII. Summary of Protective and Sensitizing Mechanisms IX. References 5. Recovery and Therapy of the Irradiated Organism I. Introduction—General Survey of Factors Influencing Recovery II. Some Physiologic Factors Influencing Recovery III. Specific Therapy of the Bone Marrow Syndrome IV. Effects of Parabiosis V. Hormones in the Treatment of Irradiated Animals VI. Specific Therapy of the Gastrointestinal Syndrome VII. Therapeutic Attempts with Miscellaneous Substances VIII. Conclusion IX. References Author Index Subject Index