Mechanisms in Bioenergetics - 1st Edition - ISBN: 9780125746625, 9781483268934

Mechanisms in Bioenergetics

1st Edition

Authors: Efraim Racker
Editors: Anthony San Pietro
eBook ISBN: 9781483268934
Imprint: Academic Press
Published Date: 1st January 1965
Page Count: 272
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Advanced Biochemistry: Mechanisms in Bioenergetics provides information pertinent to the fundamental aspects of the mechanisms in bioenergetics. This book covers a variety of topics, including the enzymatic mechanism of ATP formation and the regulatory mechanisms that control its metabolic utilization.

Organized into three parts encompassing 18 lectures, this book begins with an overview of the process of converting nutrients into forms of useful energy, which is the essence of energy metabolism. This text then explores the properties that have a specific bearing on the problem of oxidative phosphorylation. Other lectures consider the phosphoroclastic reaction with pyruvate, which plays a curious and apparently specific role in nitrogen fixation. This book discusses as well the operation of control mechanisms of energy metabolism in intact cells. The final lecture analyzes the rate-limiting steps in carbohydrate metabolism of various cells and some of the metabolic factors that govern them.

This book is a valuable resource for graduate students.

Table of Contents



Reference Abbreviations

Part I Formation of Adenosine Triphosphate in Soluble Systems

Lecture 1 General Considerations of Energy Production

Substrate Level Oxidative Phosphorylation

Phosphoroclastic Reactions

Dehydration of 2-Phosphoglycerate Catalyzed by Enolase

Oxidative Phosphorylation and Photophosphorylation

Lecture 2 Substrate Level Oxidative Phosphorylation (A)

Oxidation of Glyceraldehyde 3-Phosphate

Lecture 3 Substrate Level Oxidative Phosphorylation (B)

Oxidation of Glyceraldehyde 3-Phosphate

Lecture 4 Substrate Level Oxidative Phosphorylation (C)

Oxidation of Acetaldehyde in Bacteria

Aspartic Semialdehyde Dehydrogenase

Oxidation of α-Ketoglutarate and Pyruvate

Other Variants

Lecture 5 Phosphoroclastic Reactions: Phosphoketolase


Lecture 6 Other Phosphoroclastic Reactions

Reactions with Pyruvate

Phosphorolysis of a C—N Bond

Phosphorolysis of Thiol Esters

Dehydration of 2-Phosphoglycerate Catalyzed by Enolase

Part II Formation of Adenosine Triphosphate in Particulate Systems

Lecture 7 Oxidative Phosphorylation in Mitochondria

Stages of Discovery

Mitochondrial Enzymes

Lecture 8 The Respiratory Chain

Cytochromes 𝒂 and 𝒂3

Cytochrome 𝒄

Cytochrome 𝒄1

Cytochrome 𝒃


Pyridine Nucleotides

Ubiquinone-Coenzyme 𝑄


Structural Protein

Electron Carriers


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© Academic Press 1965
Academic Press
eBook ISBN:

About the Author

Efraim Racker

About the Editor

Anthony San Pietro

Affiliations and Expertise

Indiana University, Bloomington, Indiana, U.S.A.

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