Mechanisms in Bioenergetics - 1st Edition - ISBN: 9780125746625, 9781483268934

Mechanisms in Bioenergetics

1st Edition

Authors: Efraim Racker
Editors: Anthony San Pietro
eBook ISBN: 9781483268934
Imprint: Academic Press
Published Date: 1st January 1965
Page Count: 272
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Description

Advanced Biochemistry: Mechanisms in Bioenergetics provides information pertinent to the fundamental aspects of the mechanisms in bioenergetics. This book covers a variety of topics, including the enzymatic mechanism of ATP formation and the regulatory mechanisms that control its metabolic utilization.

Organized into three parts encompassing 18 lectures, this book begins with an overview of the process of converting nutrients into forms of useful energy, which is the essence of energy metabolism. This text then explores the properties that have a specific bearing on the problem of oxidative phosphorylation. Other lectures consider the phosphoroclastic reaction with pyruvate, which plays a curious and apparently specific role in nitrogen fixation. This book discusses as well the operation of control mechanisms of energy metabolism in intact cells. The final lecture analyzes the rate-limiting steps in carbohydrate metabolism of various cells and some of the metabolic factors that govern them.

This book is a valuable resource for graduate students.

Table of Contents


Preface


Abbreviations


Reference Abbreviations


Part I Formation of Adenosine Triphosphate in Soluble Systems


Lecture 1 General Considerations of Energy Production


Substrate Level Oxidative Phosphorylation


Phosphoroclastic Reactions


Dehydration of 2-Phosphoglycerate Catalyzed by Enolase


Oxidative Phosphorylation and Photophosphorylation


Lecture 2 Substrate Level Oxidative Phosphorylation (A)


Oxidation of Glyceraldehyde 3-Phosphate


Lecture 3 Substrate Level Oxidative Phosphorylation (B)


Oxidation of Glyceraldehyde 3-Phosphate


Lecture 4 Substrate Level Oxidative Phosphorylation (C)


Oxidation of Acetaldehyde in Bacteria


Aspartic Semialdehyde Dehydrogenase


Oxidation of α-Ketoglutarate and Pyruvate


Other Variants


Lecture 5 Phosphoroclastic Reactions: Phosphoketolase


Phosphoketolase


Lecture 6 Other Phosphoroclastic Reactions


Reactions with Pyruvate


Phosphorolysis of a C—N Bond


Phosphorolysis of Thiol Esters


Dehydration of 2-Phosphoglycerate Catalyzed by Enolase


Part II Formation of Adenosine Triphosphate in Particulate Systems


Lecture 7 Oxidative Phosphorylation in Mitochondria


Stages of Discovery


Mitochondrial Enzymes


Lecture 8 The Respiratory Chain


Cytochromes 𝒂 and 𝒂3


Cytochrome 𝒄


Cytochrome 𝒄1


Cytochrome 𝒃


Flavoproteins


Pyridine Nucleotides


Ubiquinone-Coenzyme 𝑄


Phospholipids


Structural Protein


Electron Carriers

Details

No. of pages:
272
Language:
English
Copyright:
© Academic Press 1965
Published:
Imprint:
Academic Press
eBook ISBN:
9781483268934

About the Author

Efraim Racker

About the Editor

Anthony San Pietro

Affiliations and Expertise

Indiana University, Bloomington, Indiana, U.S.A.

Ratings and Reviews