Mechanical Circulatory Support: A Companion to Braunwald's Heart Disease

1st Edition

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Key Features

  • Access the fully searchable text online at
  • Tap into discussions of hot topics in mechanical circulatory support (MCS), including current types of devices and clinical settings for MCS; MCS for pediatric and congenital heart disease; myocardial recovery, regenerative therapy, bleeding and thrombosis with MCS; cellular, molecular, genomic, and functional changes that occur in the failing heart in response to MCS; and Interagency Registry of Mechanically Assisted Circulatory Support (INTERMACS) as a tool to track and advance clinical practice.
  • Get a complete picture of the role of mechanical circulatory support in treatment through coverage of device construction, clinical applications, socioeconomic implications, and future directions.
  • Master the pathophysiology and rationale of treatment with discussions of basic science in addition to clinically-relevant information and current clinical practice guidelines.
  • Apply the expertise of the world’s most prominent leaders in mechanical circulatory support.

Table of Contents


Mechanical Circulatory Support: A Companion to Braunwald’s Heart Disease


1. Historical Aspects of Mechanical Circulatory Support

2. The Potential Population for Chronic Use of Mechanical Circulatory Support

3. Acute Decompensated Heart Failure

4. Chronic Stage D Heart Failure

5. Risk Factors for Mortality with Heart Failure

6. Candidate Selection for Chronic Left Ventricular Assist Device Therapy for Advanced Heart Failure

7. Preoperative Patient Optimization for Mechanical Circulatory Support

8. Current Types of Devices for Mechanical Circulatory Support

9. Special Clinical Settings for Mechanical Circulatory Support

10. Preoperative Anesthesia assessment/preparation

11. Surgical Methods for Mechanical Circulatory Support

12. Intraoperative Management Issues in Mechanical Circulatory Support

13. Adverse Events and Complications of Mechanical Circulatory Support

14. Pre-Discharge and Outpatient Management

15. Psychosocial and Quality of Life Issues in Mechanical Circulatory Support

16. Mechanical Circulatory Support in Pediatrics

17. Myocardial Recovery with Use of Mechanical Circulatory Support

18. Regenerative Therapy as an Adjunct to Recovery with MCS

19. Biologic Responses to the Interface Between Device and Circulation: Bleeding and Thrombosis with MCS

20. Cellular, Molecular, Genomic, and Functional Changes that Occur in the Failing Heart in Response to Mechanical Circulatory Support

21. Results of Clinical Trials to Date

22. Design Challenges for Clinical Trials in Mechanical Circulatory Support

23. Regulatory Framework for


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© 2012
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