Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic. Ocular Motor Plant and Gaze Stabilization Mechanisms

Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic. Ocular Motor Plant and Gaze Stabilization Mechanisms

1st Edition - June 21, 2019

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  • Editors: R John Leigh, Stefano Ramat, AASEF Shaikh
  • Hardcover ISBN: 9780444642332
  • eBook ISBN: 9780444642349

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Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic. Ocular Motor Plant and Gaze Stabilization Mechanisms, Volume 248, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Mathematical modeling in clinical and basic motor neuroscience, The math of medicine - the computational lessons learned from the human disease, Mathematical models - an extension of the clinician's mind, From differential equation to linear control systems: the study of the VOR, Closed lop and nonlinear systems, State-space equations and learning, Integrators and optimal control, and much more.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Progress in Brain Research series
  • Includes the latest information on mathematical modeling in motor neuroscience


Postgraduates and researchers in the area of mathematical modelling, motor neuroscience and neuroscience in general

Table of Contents

  • Section I - View of the field: Past present and future
    1. Mathematical models and human disease
    Lance M. Optican and Elena Pretegiani
    2. Mathematical models: An extension of the clinician's mind
    R. John Leigh and David S. Zee

    Section II - Didactic: Modeling
    3. Understanding the rotational vestibular ocular reflex: From differential equations to Laplace transforms
    Stefano Ramat
    4. Integration of past and current visual information during eye movements in amblyopia
    Nicolas Deravet, Demet Yüksel, Jean-Jacques Orban de Xivry and Philippe Lefèvre
    5. Mathematical models for dynamic, multisensory spatial orientation perception
    Torin K. Clark, Michael C. Newman, Faisal Karmali, Charles M. Oman and Daniel M. Merfeld

    Section III - Didactic: Translational
    6. Non-commutative, nonlinear, and non-analytic aspects of the ocular motor plant
    Joseph L. Demer
    7. Clinical applications of control systems models: The neural integrators for eye movements
    Shirin Sadeghpour, David S. Zee and R. John Leigh

    Section IV - Research: Plant and binocular control
    8. Translation and eccentric rotation in ocular motor modeling
    Joseph L. Demer and Robert A. Clark
    9. Extraocular muscles involved in convergence are innervated by an additional set of palisade endings that may differ in their excitability: A human study
    Karoline Lienbacher, Kathrin Sänger, Sebastian Strassburger, Oliver Ehrt, Günther Rudolph, Miriam Barnerssoi and Anja K.E. Horn
    10. On the retinal correspondences across the binocular visual field
    Bernhard J.M. Hess
    11. Motion and binocular disparity processing: Two sides of two different coins
    Christian Quaia, Edmond J FitzGibbon, Lance M Optican and Bruce G Cumming
    12. Non-linearity in gaze holding: Experimental results and possible mechanisms
    Giovanni Bertolini, Fausto Romano, Nina Feddermann, Dominik Straumann, Alexander Andrea Tarnutzer and Stefano Ramat
    13. Is infantile esotropia subcortical in origin?
    Michael C. Brodsky

    Section V - Research: Vestibular, balance, and postural control
    14. The influence of target distance on perceptual self-motion thresholds and the vestibulo-ocular reflex during interaural translation
    Susan King, Cyril Benoit and Faisal Karmali
    15. Spatial orientation: Model-based approach to multi-sensory mechanisms
    Amir Kheradmand and Jorge Otero-Millan
    16. Theoretical framework for "unexplained" dizziness in the elderly: The role of small vessel disease
    Diego Kaski, Heiko M. Rust, Richard Ibitoye, Qadeer Arshad, John H.J. Allum and
    Adolfo M. Bronstein
    17. The functional head impulse test: Comparing gain and percentage of correct answers
    Maurizio Versino, Silvia Colnaghi, Giulia Corallo, Marco Mandalà and Stefano Ramat
    18. Vestibular roll tilt thresholds partially mediate age-related effects on balance
    Sinem Balta Beylergil, Faisal Karmali, Wei Wang, Maria Carolina Bermúdez Rey and Daniel M. Merfeld
    19. The velocity storage time constant balances between accuracy and precision
    Faisal Karmali
    20. Toward dynamic modeling of visual-vestibular conflict detection
    Isabelle T. Garzorz and Paul R. MacNeilage
    21. A conceptual model of the visual control of posture
    Adolfo M. Bronstein
    22. Computational neurology of gravity perception involving semicircular canal dysfunction in unilateral vestibular lesions
    Stefan Glasauer, Marianne Dieterich and Thomas Brandt
    23. Effect of motor and sensory noise in the control of upright standing
    Amel Cherif, Ian Loram and Jacopo Zenzeri
    24. Model of optokinetic responses involving two different visual motion processing pathways
    Kenichiro Miura, Aya Takemura, Masakatsu Taki and Kenji Kawano

Product details

  • No. of pages: 366
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: June 21, 2019
  • Imprint: Academic Press
  • Hardcover ISBN: 9780444642332
  • eBook ISBN: 9780444642349

About the Serial Volume Editors

R John Leigh

John Leigh worts at Case Western Reserve University in Cleveland.

Affiliations and Expertise

Case Western Reserve University, Cleveland, OH, USA

Stefano Ramat

Stefano Ramat currently works at the Dip. Ingegneria Industriale e dell'Informazione, University of Pavia. Stefano does research in Bioengineering, Motor Neuroscience, Algorithms, Artificial Neural Network and Medical Devices. Their current project is 'Functional Vestibular Testing'

Affiliations and Expertise

Professor of Bioengineering, University of Pavia, Italy

AASEF Shaikh

Aasef G. Shaikh works at University Hospitals Cleveland Medical Center in Cleveland.

Affiliations and Expertise

University Hospitals Cleveland Medical Center, Cleveland, USA

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