Maternal-Fetal and Neonatal Endocrinology

Maternal-Fetal and Neonatal Endocrinology

Physiology, Pathophysiology, and Clinical Management

1st Edition - October 9, 2019

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  • Editors: Christopher Kovacs, Cheri Deal
  • Paperback ISBN: 9780128148235
  • eBook ISBN: 9780128148242

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Description

Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management systematically examines the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This reference volume expands coverage of specific disorders and diseases beyond the current endocrinology content on the market, which in most cases has a paragraph or no mention at all about pregnancy or aspects of fetal/neonatal development.

Key Features

  • Formalized source of maternal/fetal endocrine physiology and pathophysiology
  • Key reference for fellows and residents for rarer endocrine pathologies
  • Integrated presentation of new molecular and genetic causes of endocrine disorders
  • Bridges the experience/knowledge gap of endocrinopathies rarely encountered in pregnancy

Readership

Endocrinologists (adult and pediatric); obstetricians/ gynecologists; neonatologists; pediatricians; primary care physicians who provide obstetrical care; residents and fellows in the relevant specialties; translational and clinical research scientists

Table of Contents

  • Section 1: THE MOTHER
    A. Normal endocrine physiology of the mother during pregnancy and lactation
    1. Hypothalamus
    2. The pineal gland and its function in pregnancy and lactation
    3. Pituitary
    4. Physiology of the Thyroid during Pregnancy, Postpartum and Lactation
    5. Physiology of Calcium, Phosphorus, and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning
    6. Gestational Glucose Metabolism: Focus on the Role & Mechanisms of Insulin Resistance
    7. Intestinal and neuroendocrine hormones
    8. Adrenal cortex and medulla physiology during pregnancy, labor and puerperium
    9. Ovarian Function During Pregnancy and Lactation
    10. The physiological roles of the renin angiotensin aldosterone system and vasopressin in human pregnancy
    11. Central role of adipose tissue in pregnancy and lactation
    12. Hormonal regulation of the menstrual cycle and ovulation
    13. Maintenance of pregnancy and parturition
    14. Hormonal regulation of milk production
    15. Postpartum Lactational Amenorrhea and Recovery of Reproductive Function and Normal Ovulatory Menstruation

    B. Maternal endocrine disorders during pregnancy and lactation
    16. Hypothalamic
    17. Pineal
    18. Pituitary disorders (hyper and hypofunction, tumors)
    19. Thyroid (hyperthyroidism, hypothyroidism)
    20. Thyroid Cancer during Pregnancy and Lactation
    21. Disorders of Mineral and Bone Metabolism During Pregnancy and Lactation
    22. Gestational and type 2 diabetes
    23. Type 1 Diabetes: During preconception, pregnancy, postpartum, breastfeeding
    24. Gut and pancreatic neuroendocrine tumors in pregnancy and lactation
    25. Adrenal pathologies during pregnancy and post-partum
    26. Hypertension in pregnancy
    27. Obesity

    C. Other
    28. Fertility, pregnancy, and chest feeding in transgendered individuals

    Section 2: THE CHILD
    D. Normal endocrine development and physiology of the fetus and neonate
    29. Endocrinology of implantation
    30. Hypothalamus and pituitary
    31. Pineal
    32. Thyroid
    33. Physiology of Calcium, Phosphorus, and Bone Metabolism During Fetal and Neonatal Development
    34. Developmental Physiology of Carbohydrate Metabolism and the Pancreas
    35. Developmental Origins and Roles of Intestinal Enteroendocrine Hormones
    36. Adrenal cortex and medulla
    37. Ovaries and Testes
    38. Renin-angiotensin-aldosterone system and vasopressin
    39. Origins of Adipose Tissue and Adipose Regulating Hormones
    40. Fetal growth physiology
    41. Placental production of steroid and peptide hormones

    E. Endocrine disorders affecting the fetus or neonate
    42. Hypothalamus and pituitary
    43. Pineal
    44. Thyroid (agenesis, hypothyroidism, fetal Graves’, etc.)
    45. Disorders of Calcium, Phosphorus and Bone Metabolism During Fetal and Neonatal Development
    46. Pancreas and carbohydrate metabolism (diabetes and hypoglycemia)
    47. Intestinal enteroendocrine disorders
    48. Adrenal disorders of the fetus and neonate
    49. Disorders of Sex Differentiation
    50. Renin-angiotensin-aldosterone and vasopressin
    51. Obesity / perinatal origins of obesity
    52. Fetal growth failure
    53. New Technologies in Pre- and Post-natal Diagnosis

Product details

  • No. of pages: 1038
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: October 9, 2019
  • Imprint: Academic Press
  • Paperback ISBN: 9780128148235
  • eBook ISBN: 9780128148242

About the Editors

Christopher Kovacs

Christopher S. Kovacs, MD, is a Professor of Medicine (Endocrinology and Metabolism), Obstetrics & Gynecology, and BioMedical Sciences at Memorial University of Newfoundland, Canada. He obtained his MD and trained in Internal Medicine at Queen’s University, and did his clinical fellowship in Endocrinology and Metabolism at the University of Alberta. Dr. Kovacs did a postdoctoral research fellowship in bone and mineral metabolism at Harvard Medical School and Massachusetts General Hospital. His clinical practice focuses on osteoporosis, disorders of bone metabolism, thyroid disorders, and general endocrinology. His basic, translational, and clinical research focuses on adaptations in calcium and bone metabolism that occur during reproduction and fetal development. Dr. Kovacs has received over a dozen national and international awards for excellence in research, including the 2003 Gold Medal in Medicine from the Royal College of Physicians and Surgeons of Canada; the 2003 Young Investigator Award from the Canadian Society of Endocrinology and Metabolism, and Young Investigator Awards from the American Society for Bone and Mineral Research and Advances in Mineral Metabolism (AIMM). He is also past President of AIMM.

Affiliations and Expertise

Professor of Medicine (Endocrinology and Metabolism), Obstetrics & Gynecology and BioMedical Sciences at Memorial University of Newfoundland, Canada

Cheri Deal

Cheri L. Deal, PhD, MD, is a Professor of Endocrinology in the Department of Pediatrics, University of Montreal, and the Chief of the Endocrinology Service at the Ste-Justine Mother-Child University Teaching Hospital in Montreal, Canada. Her training took her to McGill University, University of Montreal, and finally Stanford University for her endocrine research fellowship in placental growth. Past President of both the Canadian Pediatric Endocrine Group and the Canadian Society of Endocrinology and Metabolism, she now chairs the Education Committee of the International Society of Endocrinology. Her awards include the Young Investigator Award from the Pediatric Endocrine Society (previously LWPES), and most recently the Harvey Guyda Educator of the Year Award and the Robert Volpé Service Award from the Canadian Society of Endocrinology and Metabolism. Her major research interest is in the contribution of the growth hormone-insulin-like growth factor (GH-IGF) axis to the regulation of human growth. She has a strong commitment to patient-driven research, and has helped to elucidate the molecular defects associated with a wide range of rare pediatric endocrine disorders as well as participated in clinical studies aimed at ameliorating outcomes in a variety of pediatric endocrine diseases.

Affiliations and Expertise

Professor of Endocrinology in the Department of Pediatrics, University of Montreal Chief of the Endocrinology Service at the Ste-Justine Mother-Child University Teaching Hospital, Montreal, Canada Chair of the Education Committee of the International Society of Endocrinology

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