Mass Spectrometry

Mass Spectrometry: Techniques for the Structural Characterization of Glycans presents new methods for conducting detailed carbohydrate qualitative analysis—arming analytical chemists, pharmaceutical scientists, and food scientists with a quick reference that will allow them to determine the structures of carbohydrates molecules.

As there is a need in the scientific community for content specific to structural determination and analysis of new glycoprotein drug, and because structure-activity analysis requires a structural determination of the N- and O-linked oligosaccharides linked to glycol-proteins, this book provides the relevant research that are necessary for advances and new outcomes in this area of study.

• Authored by an analytical chemist with more than 30 years of experience in research and industry
• Serves as a quick reference in mass spectral analysis and carbohydrates
• Includes more than 60 figures to aid in the retention of key concepts

Analytical chemists, pharmaceutical scientists, and food scientists conducting research in mass spectral analysis.

• Dedication
• Mass Spectral Analysis of Carbohydrates
  • Abstract
  • 1 Isolation Methods for MS Analysis
  • 2 Component Monosaccharide Analysis by Acid Catalyzed Hydrolysis of Glycan and Qualitative Chromatographic Identification by HPLC
  • 3 Identification of Glycoses Versus Glycitols by HPAEC-PAD Difference Chromatograms
  • 4 The Methods for Preparing an Oligosaccharide Reducing Glycan from a Glycoprotein, Linked Through O-Glycosidic Linkage
  • Conclusions
  • References