Mass Spectrometry

Mass Spectrometry

Techniques for Structural Characterization of Glycans

1st Edition - May 6, 2016

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  • Author: Mike Madson
  • eBook ISBN: 9780128041352
  • Hardcover ISBN: 9780128041291

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Mass Spectrometry: Techniques for the Structural Characterization of Glycans presents new methods for conducting detailed carbohydrate qualitative analysis—arming analytical chemists, pharmaceutical scientists, and food scientists with a quick reference that will allow them to determine the structures of carbohydrates molecules. As there is a need in the scientific community for content specific to structural determination and analysis of new glycoprotein drug, and because structure-activity analysis requires a structural determination of the N- and O-linked oligosaccharides linked to glycol-proteins, this book provides the relevant research that are necessary for advances and new outcomes in this area of study.

Key Features

  • Authored by an analytical chemist with more than 30 years of experience in research and industry
  • Serves as a quick reference in mass spectral analysis and carbohydrates
  • Includes more than 60 figures to aid in the retention of key concepts


Analytical chemists, pharmaceutical scientists, and food scientists conducting research in mass spectral analysis.

Table of Contents

    • Dedication
    • Mass Spectral Analysis of Carbohydrates
      • Abstract
      • 1 Isolation Methods for MS Analysis
      • 2 Component Monosaccharide Analysis by Acid Catalyzed Hydrolysis of Glycan and Qualitative Chromatographic Identification by HPLC
      • 3 Identification of Glycoses Versus Glycitols by HPAEC-PAD Difference Chromatograms
      • 4 The Methods for Preparing an Oligosaccharide Reducing Glycan from a Glycoprotein, Linked Through O-Glycosidic Linkage
      • Conclusions
      • References

Product details

  • No. of pages: 86
  • Language: English
  • Copyright: © Elsevier 2016
  • Published: May 6, 2016
  • Imprint: Elsevier
  • eBook ISBN: 9780128041352
  • Hardcover ISBN: 9780128041291

About the Author

Mike Madson

Mike Madson is CEO and Senior Research Scientist of BioLogistics, LLC, Iowa, USA

Affiliations and Expertise

BioLogistics, LLC, Iowa, USA

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