
Mass Spectrometry
Techniques for Structural Characterization of Glycans
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Mass Spectrometry: Techniques for the Structural Characterization of Glycans presents new methods for conducting detailed carbohydrate qualitative analysis—arming analytical chemists, pharmaceutical scientists, and food scientists with a quick reference that will allow them to determine the structures of carbohydrates molecules. As there is a need in the scientific community for content specific to structural determination and analysis of new glycoprotein drug, and because structure-activity analysis requires a structural determination of the N- and O-linked oligosaccharides linked to glycol-proteins, this book provides the relevant research that are necessary for advances and new outcomes in this area of study.
Key Features
- Authored by an analytical chemist with more than 30 years of experience in research and industry
- Serves as a quick reference in mass spectral analysis and carbohydrates
- Includes more than 60 figures to aid in the retention of key concepts
Readership
Analytical chemists, pharmaceutical scientists, and food scientists conducting research in mass spectral analysis.
Table of Contents
- Dedication
- Mass Spectral Analysis of Carbohydrates
- Abstract
- 1 Isolation Methods for MS Analysis
- 2 Component Monosaccharide Analysis by Acid Catalyzed Hydrolysis of Glycan and Qualitative Chromatographic Identification by HPLC
- 3 Identification of Glycoses Versus Glycitols by HPAEC-PAD Difference Chromatograms
- 4 The Methods for Preparing an Oligosaccharide Reducing Glycan from a Glycoprotein, Linked Through O-Glycosidic Linkage
- Conclusions
- References
Product details
- No. of pages: 86
- Language: English
- Copyright: © Elsevier 2016
- Published: May 6, 2016
- Imprint: Elsevier
- eBook ISBN: 9780128041352
- Hardcover ISBN: 9780128041291
About the Author
Mike Madson
Mike Madson is CEO and Senior Research Scientist of BioLogistics, LLC, Iowa, USA
Affiliations and Expertise
BioLogistics, LLC, Iowa, USA