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Manual of Pediatric Hematology and Oncology - 5th Edition - ISBN: 9780123751546, 9780123751553

Manual of Pediatric Hematology and Oncology

5th Edition

Editor: Philip Lanzkowsky
eBook ISBN: 9780123751553
Hardcover ISBN: 9780123751546
Imprint: Academic Press
Published Date: 6th June 2005
Page Count: 1058
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Given that there have been considerable advances in the treatment and management of oncologic diseases in children, the fifth edition of this successful clinical manual will be entirely updated to incorporate all current protocols and developments.This edition will be a comprehensive book on patient management, replete with algorithms and flow diagrams on diagnosis and management. Its concise and easy-to-read format will enable readers to make accurate diagnoses and permit them to treat patients without having extensive previous hematologic/oncologic experience. A list of normal values at various ages in children, providing an extremely useful reference for patient management is included.

Key Features

  • Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries
  • Offers a concise, systematic approach to all pediatric hematologic and oncologic disorders in one reference manual
  • Easy-to-read format: multiple tables, charts, and flow-diagrams for diagnosis and management of pediatric hematologic and oncologic disorders
  • Clear presentation by practicing clinicians, who are also academic researchers, of recent developments in molecular genetics, cytogenetics, immunology, transplantation, and biochemistry


Medical students, pediatric residents, pediatric fellows in hematology/oncology, practicing hematologists and oncologists pediatric oncology nurses, nurse practitioners and physician assistants

Table of Contents

Chapter 1

Classification & Diagnosis of Anemia during Childhood

Philip Lanzkowsky

Chapter 2

Anemia During the Neonatal Period

Philip Lanzkowsky

Chapter 3

Iron-Deficiency Anemia

Philip Lanzkowsky

Chapter 4

Magaloblastic Anemia

Philip Lanzkowsky

Chapter 5

Hematologic Manifestations of System Illness

Lawrence Wolfe

Chapter 6

Bone Marrow Failure

Jeff Lipton

Chapter 7

Hemolytic Anemia due to Membrane & Enzyme Defects

Lawrence Wolfe

Chapter 8

Hemoglobinopathies…. Sickle Cell Disease/ Thalassemia

Janet Kwiatkowski

Chapter 9

Extracorpuscular Hemolytic Disease

Lawrence Wolfe

Chapter 10


Josef Thomas Prchal

Chapter 11

Disorders of the White Blood Cells

Jill S. Menell

Chapter 12

Disorders of Platelets

James B. Bussel

Chapter 13

Hemostatic Disorders

Suchritra Acharya

Chapter 14

Thrombotic Disorders

Suchritra Acharya

Chapter 15

Lymphadenopathy and Splenomegaly

Philip Lanzkowsky

Chapter 16

Lymphoproliferative Disorders, Myelodysplastic Syndromes, Myeloprof Dis

David T. Teachey

Chapter 17


Arlene Redner

Chapter 18

Histiocytosis Syndromes

Robert J. Arceci

Chapter 19

Hodgkin's Disease

Debra L. Friedman

Chapter 20

Non-Hodgkin Lymphoma

Mitchell Cairo

Chapter 21

Central Nervous System Malignancies

Mark Atlas

Chapter 22


Julie R. Park

Chapter 23

Wilms' Tumor

Jeffrey Stuart Dome

Chapter 24

Rhabdomyosarcoma&Other Soft Tissue Sarcomas

Carolyn Fein-Levy

Chapter 25

Malignant Bone Tumors

Neyssa Marina

Chapter 26


Debra L. Friedman

Chapter 27

Germ Cell Tumors

Thomas Olson

Chapter 28

Primary Hepatic Tumors

Thomas Olson

Chapter 29

Hematopoietic Stem Cell Transplantation


Chapter 30

Management of Oncologic Emergencies

Susan R. Rheingold

Chapter 31

Supportive Care of Patients with Cancer

Lawrence Wolfe

Chapter 32

Eval, Investigations & Management of Late Effects of Childhood Cancer

Jonathan Fish

Chapter 33

Psycho-Social Aspects of Managing Oncologic Patients

Lori S. Wiener


No. of pages:
© Academic Press 2010
6th June 2005
Academic Press
eBook ISBN:
Hardcover ISBN:

About the Editor

Philip Lanzkowsky

Dr. Philip Lanzkowsky was born in Cape Town on March 17, 1932 and graduated high school from the South African College and obtained his MB ChB degree from the University of Cape Town School of Medicine in 1954 and his Doctorate degree in 1959 for his thesis on Iron Deficiency Anemia In Children. He completed a pediatric residency at the Red Cross War Memorial Children’s Hospital in Cape Town in 1960. After working in Pediatrics at the University of Edinburgh and at St Mary’s Hospital of the University of London, Dr. Lanzkowsky did a pediatric Hematology-Oncology fellowship at Duke University School of Medicine and at the University of Utah. In 1963 he was appointed Consultant Pediatrician and Pediatric Hematologist to the Red Cross War Memorial Children’s Hospital at the University of Cape Town and introduced Pediatric Hematology and Oncology as a distinct discipline. In 1965 he was appointed Director of Pediatric Hematology and Associate Professor of Pediatrics at the New York Hospital-Cornell University School of Medicine. In 1970 he was appointed Professor of Pediatrics and Chairman of Pediatrics at Long Island Jewish Medical Center and established a division of Pediatric Hematology-Oncology which he directed until 2000. He was the founder of the Schneider Children’s Hospital, which he developed, planned, and was the hospital’s Executive Director and Chief of Staff from its inception in 1983 until 2010. Dr. Lanzkowsky has received numerous honors and awards and has lectured extensively at various institutions and medical schools in the United States and around the world. In addition to having been the author of five editions of the Manual of Pediatric Hematology and Oncology used by clinicians worldwide, he is the author of How It All Began: The History of a Children’s Hospital and over 280 scientific papers, abstracts, monographs, and book chapters. Dr. Lanzkowsky’s medical writings have been prodigious. His seminal contributions to the medical literature have included the first description of the relationship of pica to iron-deficiency anemia (Arch. Dis Child., 1959), Effects of timing of clamping of umbilical cord on infant’s hemoglobin level (Br. Med. J., 1960), Normal oral D-xylose test values in children (New Engl. J. Med., 1963), Normal coagulation factors in women in labor and in the newborn (Thromboses at Diath. Hemorr., 1966), Erythrocyte abnormalities induced by malnutrition (Br. J. Haemat., 1967), Radiologic features in iron deficiency anemia (Am. J. Dis. Child., 1968), Isolated defect of folic acid absorption associated with mental retardation (Blood, 1969; Am. J. Med, 1970), Disaccharidase levels in iron deficiency (J. Pediat., 1981) and Hexokinase “New Hyde Park” in a Chinese kindred (Am. J. Hematol., 1981).

Affiliations and Expertise

Chief Emeritus, Pediatric Hematology-Oncology, Chairman Emeritus, Department of Pediatrics, Executive Director and Chief-of-Staff (Retired), Steven and Alexandra Cohen Children's Medical Center, New Hyde Park, NY, USA, Vice President, Children's Health Network (Retired), North Shore-Long Island Jewish Health System, Consultant, Steven and Alexandra Cohen Children's Medical Center of New York, Professor of Pediatrics, Hofstra Northwell School of Medicine, Hempstead, NY, USA


Doody’s Core Titles 2013, Doody Enterprises



"This text is a very good intermediate level book focusing on the clinical presentation, diagnosis, and management of both hematologic and oncologic disorders observed in children. The combination of text, tables, and outlined material makes the information easy to access. It provides a handy text for pediatricians caring for both hematologic and oncologic problems. It also is particularly suitable for pediatric students and residents. The comprehensive tables of normal values in infants and children at the end of the text are very useful."
- Marshall Lichtman, URMC, Rochester (2005)



"This Manual is an amazing amalgam of an extremely practical workbook and also more than a bird's eye-view of the entire scope of pediatric hematology-oncology. In my opinion, this Manual is a "must-have" book for three distinct and important potential users: clinicians in practice, residents and fellows in training, and medical students. Dr. Philip Lanzkowsky deserves congratulations for this authoritative and yet highly accessible text."

—Kanti R. Rai, MD, Chief, Division of Hematology-Oncology, Long Island Jewish Medical Center, Professor of Medicine, Albert Einstein College of Medicine, New York, USA

"The Fifth Edition of the Manual of Pediatric Hematology and Oncology constitutes an evolutionary leap from previous editions. In addition to an instructive manual containing the body of information required as background for the numerous informative and clearly organized tables, algorithms and instructions, the present extensive and thoughtfully produced book is also a source of scientific and clinical learning on the broad spectrum of subjects that make up pediatric hematology and oncology – in this era of rapid, and often bewildering, developments.

The style is clear and authoritative, attesting to what the editor's colleagues and disciples call "the Lanzkowsky way of teaching." The contributors are internationally known experts in their various subjects, and the material is admirably up to date. This edition is of great value not only to pediatric teams of hematologists and oncologists, but also to pediatric practitioners in general."

—Moshe Berant, MD, Professor (Emeritus) of Pediatrics, Rambam Health Care Campus and Technion-Faculty of Medicine, Israel

"I would not be without this book and have been recommending it to postgraduate students in paediatrics and paediatric haematology and oncology for a number of years. It is packed with up-to-date, concise and practical information. The detailed tables and algorithms are extremely useful both as teaching and management tools.

I was particularly impressed with the expanded information on haemaglobinopathies and haematologic manifestations of infectious diseases in this 5th edition. This book should be on the shelves of all paediatricians and paediatric haematologists."

—Prof. Patricia Hartley, MD, Emeritus Head of Paediatric Haematology and Oncology, School of Child and Adolescent Health, University of Cape Town, South Africa

Ratings and Reviews