Management of Endocrine Tumors, An Issue of Surgical Oncology Clinics of North America

Cover image

Title page

Table of Contents

Copyright

Contributors

Forthcoming Issues

Foreword

Preface

A Contemporary Review of the Treatment of Medullary Thyroid Carcinoma in the Era of New Drug Therapies

Key points

Introduction

Pathobiology of medullary thyroid cancer

Diagnosis and optimal imaging strategy

Surgical management of medullary thyroid cancer

Adjuvant therapy for medullary thyroid cancer

Prognostic factors for medullary thyroid cancer

Targeted therapy

Surveillance

Treatment for persistent or recurrent disease

Summary

A Nomogram for Relapse/Death and Contemplating Adjuvant Therapy for Parathyroid Carcinoma

Introduction

Discussion

Summary

Clinics care points

Parathyroid Cancer: Updates and Postoperative Surveillance Imaging

Key points

Parathyroid carcinoma—frequently considered, rarely encountered

Genetics

Prognosis of parathyroid carcinoma

Follow-up protocols after resection of parathyroid carcinoma

Summary

Clinics care points

Adrenocortical Carcinoma: Role of Adjuvant and Neoadjuvant Therapy

Key points

Introduction

Discussion

Summary

Clinics care points

Succinate Dehydrogenase Mutations as Familial Pheochromocytoma Syndromes

Key points

Introduction

Genetic testing

Preoperative management

Surgical management

Summary

Clinics care points

Genetic Testing for Adrenal Tumors—What the Contemporary Surgeon Should Know

Key points

Introduction

Pheochromocytoma and paraganglioma

Primary hyperaldosteronism

Cortisol-producing adrenal syndromes

Adrenocortical carcinoma

Summary

Disclosure

Multiple Endocrine Neoplasia Type 1 Syndrome Pancreatic Neuroendocrine Tumor Genotype/Phenotype: Is There Any Advance on Predicting or Preventing?

Key points

Multiple endocrine neoplasia type 1 syndrome: prevalence and diagnosis

Multiple endocrine neoplasia type 1 syndrome: menin

Multiple endocrine neoplasia type 1 syndrome: clinical manifestations

Pancreatic neuroendocrine tumors

Genotype–phenotype correlations in multiple endocrine neoplasia type 1 syndrome-associated pancreatic neuroendocrine tumors

Epigenetic mechanisms in multiple endocrine neoplasia type 1 syndrome-associated pancreatic neuroendocrine tumors

Future directions

Summary

Minimally Invasive Pancreatectomy: Robotic and Laparoscopic Developments

Key points

Introduction

Summary

Conflicts of interest

Status of Surveillance and Nonsurgical Therapy for Small Nonfunctioning Pancreatic Neuroendocrine Tumors

Key points

Introduction

Background

Summary

Clinics care points

Lobectomy or Total Thyroidectomy—Where Is the Pendulum now for Differentiated Thyroid Cancer?

Key points

Introduction

Preoperative decision-making

Reasons in favor of a unilateral operation (thyroid lobectomy) Table 3

Reasons in favor of a bilateral operation (total thyroidectomy) Table 4

Intraoperative decision-making

Postoperative decision-making

Oncologic outcomes

Summary

Clinics care points

Disclosures/conflict of interest statement

A Nod to the Nodes: An Overview of the Role of Central Neck Dissection in the Management of Papillary Thyroid Carcinoma

Key points

Introduction

Preoperative and Intraoperative Staging of the Central Neck Compartment

Anatomy of the Central Neck Compartment

Lymphatic Drainage and Patterns of Spread

Extent of Central Neck Dissection

Lymph Node Yield

Prophylactic Neck Dissection

Summary

Disclosure