Lung Function Testing in the 21st Century

Lung Function Testing in the 21st Century

Methodologies and Tools Bridging Engineering to Clinical Practice

1st Edition - November 19, 2018

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  • Author: Clara Ionescu
  • eBook ISBN: 9780128146132
  • Paperback ISBN: 9780128146125

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Lung Function Testing in the 21st Century: Methodologies and Tools Bridging Engineering to Clinical Practice covers the complete aspects of lung function testing, ranging from standardized to newly introduced (IOS, FOT) methods. It provides an updated overview of advances in respiratory engineering, along with advice on which lung function tests are appropriate for which purpose. The author discusses non-standardized lung function testing, methods, clinical tests, diagnosis and future perspectives. Lung function measurement devices and protocols are also covered. This book covers multidisciplinary domains, bringing new technology ideas from mathematics, physics, biology and engineering into the field of respiratory engineering. Users will find a single resource that brings together all of the disparate information on lung function testing technology currently contained in many journal articles.

Key Features

  • Bridges the gap between engineers and clinicians with regard to pulmonary function techniques, from research, to design and clinical practice
  • Provides a comprehensive overview of all tools available for lung function testing, detailing their pros and cons
  • Includes information on incorporating new devices into existing procedures, along with methods for lung function testing


Biomedical Engineers working in Respiratory Engineering, and academics in the field of Respiratory Medicine

Table of Contents

  • Standardized lung function testing: spirometry and body plethysmography
    Non-standardized lung function testing:
    impulse oscillometry
    Forced oscillation technique
    Methods for extracting lung function information from time-based signals
     Respiratory impedance
     Pressure-volume, flow-volume curves
     Stress-strain curves
     Models for evaluating respiratory properties
      Integer order impedance models
      Fractional order impedance models
     Heterogeneity and nonlinearity in the lung tissue
    Diffusion in small airways
     Clinical relevance
     Evaluating diffusion
     Effects of geometry and porosity on diffusion
    Added value of other clinical tests:
    - CT scans
    - Ultrasound
    - Electrical impedance tomography (EIT)
    Diagnosis of asthma and COPD:
    - Complementary lung function tests
    - Which lung function tests for which purpose
    - Patient Monitoring and Treatment Management
    Perspectives: what we still do not know but would like to find out

Product details

  • No. of pages: 210
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: November 19, 2018
  • Imprint: Academic Press
  • eBook ISBN: 9780128146132
  • Paperback ISBN: 9780128146125

About the Author

Clara Ionescu

Prof. Dr. Clara Mihaela Ionescu is the holder of the Flanders Research Foundation FWO post-doctoral scholarship at Ghent University. She is author of more than 150 scientific papers of which more than 100 cited in Web of Science, with an h-index of 13. Currently she is involved in 5 international projects with both industrial and biomedical applications, for identification and control. She was a member of the European Respiratory Society 2006-2008 and she was the first to coin the link between fractional order impedance models for respiratory properties to actual physiology and morphology of the lungs. She is member of several technical committees of IFAC and IEEE, including domains of biomedical engineering applications.

Affiliations and Expertise

Ghent University, Belgium

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