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Lung Function Testing in the 21st Century - 1st Edition - ISBN: 9780128146125, 9780128146132

Lung Function Testing in the 21st Century

1st Edition

Methodologies and Tools Bridging Engineering to Clinical Practice

Author: Clara Ionescu
eBook ISBN: 9780128146132
Paperback ISBN: 9780128146125
Imprint: Academic Press
Published Date: 19th November 2018
Page Count: 210
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Lung Function Testing in the 21st Century: Methodologies and Tools Bridging Engineering to Clinical Practice covers the complete aspects of lung function testing, ranging from standardized to newly introduced (IOS, FOT) methods. It provides an updated overview of advances in respiratory engineering, along with advice on which lung function tests are appropriate for which purpose. The author discusses non-standardized lung function testing, methods, clinical tests, diagnosis and future perspectives. Lung function measurement devices and protocols are also covered. This book covers multidisciplinary domains, bringing new technology ideas from mathematics, physics, biology and engineering into the field of respiratory engineering.

Users will find a single resource that brings together all of the disparate information on lung function testing technology currently contained in many journal articles.

Key Features

  • Bridges the gap between engineers and clinicians with regard to pulmonary function techniques, from research, to design and clinical practice
  • Provides a comprehensive overview of all tools available for lung function testing, detailing their pros and cons
  • Includes information on incorporating new devices into existing procedures, along with methods for lung function testing


Biomedical Engineers working in Respiratory Engineering, and academics in the field of Respiratory Medicine

Table of Contents

Standardized lung function testing: spirometry and body plethysmography
Non-standardized lung function testing:
impulse oscillometry
Forced oscillation technique
Methods for extracting lung function information from time-based signals
Respiratory impedance
Pressure-volume, flow-volume curves
Stress-strain curves
Models for evaluating respiratory properties
Integer order impedance models
Fractional order impedance models
Heterogeneity and nonlinearity in the lung tissue
Diffusion in small airways
Clinical relevance
Evaluating diffusion
Effects of geometry and porosity on diffusion
Added value of other clinical tests:
- CT scans
- Ultrasound
- Electrical impedance tomography (EIT)
Diagnosis of asthma and COPD:
- Complementary lung function tests
- Which lung function tests for which purpose
- Patient Monitoring and Treatment Management
Perspectives: what we still do not know but would like to find out


No. of pages:
© Academic Press 2018
19th November 2018
Academic Press
eBook ISBN:
Paperback ISBN:

About the Author

Clara Ionescu

Prof. Dr. Clara Mihaela Ionescu is the holder of the Flanders Research Foundation FWO post-doctoral scholarship at Ghent University. She is author of more than 150 scientific papers of which more than 100 cited in Web of Science, with an h-index of 13. Currently she is involved in 5 international projects with both industrial and biomedical applications, for identification and control. She was a member of the European Respiratory Society 2006-2008 and she was the first to coin the link between fractional order impedance models for respiratory properties to actual physiology and morphology of the lungs. She is member of several technical committees of IFAC and IEEE, including domains of biomedical engineering applications.

Affiliations and Expertise

Ghent University, Belgium

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