Loomis's Essentials of Toxicology

Loomis's Essentials of Toxicology

4th Edition - March 1, 1996

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  • Authors: A. Hayes, Ted Loomis
  • eBook ISBN: 9780080535630

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Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved; the general properties of chemicals and biologic systems as they influence the occurrence of detrimental biologic effects; the methods used to demonstrate these effects; and the basis for clinical diagnosis and therapy of harmful effects of chemicals on humans. Individual examples are used to demonstrate each of the principles under discussion. This text is an invaluable resource for toxicologists as well as a comprehensive introduction to the topic for graduate and advanced undergraduate students in toxicology and public health.

Key Features

  • The "classic textbook" in toxicology
  • Completely revised and updated
  • Includes both principles and methods
  • Requires minimal background in chemistry and biology


Toxicologists and graduate and advanced undergraduate students in toxicology and public health. Also suitable as recommended/supplemental reading for some pharmacology courses

Table of Contents

  • Introduction, Scope and Principles.
    Numbers in Toxicology.
    Biologic Factors that Influence Toxicity.
    Influence of Route of Administration on Systemic Toxicity.
    Genetic Factors that Influence Toxicity.
    Classifications of Harmful Effects of Chemicals.
    Normal Toxic Effects of Chemicals.
    Normal Toxic Effects of Chemicals.
    Abnormal Response to Chemicals.
    The Basis of Selective Toxicity.
    The Basis of Antidotal Therapy.
    Principles of Biological Tests for Toxicity.
    Toxicologic Testing Methods.
    Clinical Toxicology.
    Information Sources in Toxicology.
    Subject Index.

Product details

  • No. of pages: 282
  • Language: English
  • Copyright: © Academic Press 1996
  • Published: March 1, 1996
  • Imprint: Academic Press
  • eBook ISBN: 9780080535630

About the Authors

A. Hayes

A. Wallace Hayes, PhD holds degrees from Auburn University (Ph.D. and MS) and Emory University (AB). He was an NSF predoctoral fellow at Auburn University, an NIH individual postdoctoral fellow at the Vanderbilt University School of Medicine, a NATO Senior Scientist at the Central Veterinary Laboratory in Weybridge, England, and an NIH Research Career Development Awardee. Dr. Hayes has held Professorships at the University of Alabama, the University of Mississippi Medical Center, and Wake Forest University School of Medicine. Dr. Hayes has authored more than 370 peer-reviewed publications, is the editor of Hayes’ Principles and Methods of Toxicology, 7th edition, Human and Experimental Toxicology, Cutaneous and Ocular Toxicology, Toxicology Research and Application, and the co-editor of the Target Organ Toxicity Series of books. Dr. Hayes is the Editor-in-Chief emeritus, of Food and Chemical Toxicology and the co-author of Loomis’ Essential of Toxicology, 5th Edition. Dr. Hayes is past Secretary-General of IUTOX (two terms), past board member of the American Board of Toxicology, past president of the American College of Toxicology, the Toxicology Education Foundation, and the Academy of Toxicological Sciences, the Toxicology Forum, and past member of the council of the Society of Toxicology. Dr. Hayes is a diplomate of the American Board of Toxicology, the Academy of Toxicological Sciences, the American Board of Forensic Medicine, and the American Board of Forensic Examiners. He is a Fellow of the Academy of Toxicological Sciences, the Royal Society of Biology (UK), the Royal Society of Medicine (UK), the American College of Forensic Examiners, and the American College of Nutrition. Dr. Hayes is a registered toxicologist in the European Union (ERT) and a certified nutrition specialist (food safety). Dr. Hayes was honored by the Society of Toxicology in 2006 with its Merit Award, by the Mid-Atlantic Society of Toxicology with its Ambassador Award in 2012, by the American College of Toxicology in 2012 with its Distinguished Scientist Award, and by the International Dose-Response Society in 2013 with its Outstanding Leadership Award, and by The American Academy of Toxicology with its Mildred S. Christian Career Achievement Award in 2021. Dr. Hayes was named a Distinguished Fellow by the American College of Toxicology in 2013 and a fellow of the American Association for the Advancement of Science in 2014.

Affiliations and Expertise

Adjunct Professor, Institute for Integrative Toxicology, Michigan State University, East Lansing, MI and Affiliated Professor, Center for Environmental Occupational Risk Analysis and Management, College of Public Health, University of South Florida, Tampa, FL

Ted Loomis

Dr. Ted A. Loomis, since receiving his M.D. from Yale University School of Medicine in 1946, he has had a rewarding career in Pharmacology and Toxicology. His career started with an internship at the Marine Hospital, U.S. Public Health Service, Seattle, WA in 1946. By 1953 he as serving as a Captain in the U.S. Army Medical Service. After his military service he eventually became a Professor of Pharmacology and Toxicology at the University of Washington School of Medicine until 1987, and currently is a Consulting Toxicologist. Some of his accomplishments include recipient awards for: Toxicology Education, Toxicology and Forum for Advancement of Toxicology, 1976 and Merit Award, Society of Toxicology, 1986. His professional activities include various committee memberships organizations such as: Tests for Intoxication, National Safety Council, since 1951, Agricultural Advisory Board on Pesticides and Insecticides, State of Washington, 1963-77, and Scientific Review Panel for Health Research, U.S. Environmental Protection Agency, 1980. By 1978, Dr. Loomis had published three editions of Essentials of Toxicology, Lea & Febiger, Philadelphia. He has also been the author or co-author of approximately 100 papers in the scientific literature.

Affiliations and Expertise

University of Washington School of Medicine, Seattle, U.S.A.

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