Looking at Ribozymes - 1st Edition - ISBN: 9781785482106

Looking at Ribozymes

1st Edition

From Atomic to Molecular and Cellular Scales

Authors: Fabrice Leclerc Benoît Masquida
Hardcover ISBN: 9781785482106
Imprint: ISTE Press - Elsevier
Published Date: 1st June 2018
Page Count: 130
Tax/VAT will be calculated at check-out Price includes VAT (GST)

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

Looking at Ribozymes: From Atomic to Molecular and Cellular Scales introduces ideas on how ribozymes “work” through a comparison of their common features and specificities. How they work is not just a matter of enzymatic catalysis, but to a more granular level, how do the (macro) molecular organization at different scales make it possible, what function do they carry, where are they found, how did they evolve, and how have they been used? The book emphasizes common and specific features of natural and artificial ribozymes, from the basics, to more advanced aspects, making it ideal for undergraduates, grad students and researchers.

Specific sections cover different areas of research, from the atomic scale (catalysis), to the molecular (folding, dynamics), macromolecular and cellular scales (dynamics, long-range interactions, self-assembly, cellular processes). The book is not a directory of ribozymes, instead providing comparative knowledge, including the inter-dependent relationships between the different scales of description based on different experimental and theoretical approaches.

Key Features

  • Provides a comparative knowledge of ribozymes based on scales of organization and description
  • Covers different areas of research, from the atomic scale (catalysis), to the molecular (folding, dynamics), macromolecular and cellular scales
  • Includes the inter-dependent relationships between the different scales of description based on different experimental and theoretical approaches

Readership

Undergraduate and PhD students, scientists working in the fields of ribozymes, RNA, catalysis and enzymes. Scientists interested in the fields of RNA and evolution

Table of Contents

Introduction. A small history of a ribozyme prototype (the hammerhead ribozyme)
1. RNA: from non-enzymatic to enzymatic catalysis
2. Catalytic diversity in ribozyme subclasses
3. Folding, structure and dynamics of ribozymes
4. Long-range interactions and macromolecular assemblies
5. Molecular adaptation during evolution
6. Ribozymes in Cellular Processes: from viroids to eukaryotes
7. Natural and artificial ribozymes: evolution and design

Details

No. of pages:
130
Language:
English
Copyright:
© ISTE Press - Elsevier 2018
Published:
Imprint:
ISTE Press - Elsevier
Hardcover ISBN:
9781785482106

About the Author

Fabrice Leclerc

Fabrice Leclerc is a research fellow at the French National Centre for Scientific Research, Paris with expertise in Biophysics, Bioinformatics and Structural Biology

Affiliations and Expertise

Institute for Integrative Biology of the Cell (I2BC), Dept. Genome Biology, CNRS-CEA-Université Paris Sud

Benoît Masquida

Benoît Masquida is a research fellow at the Institut de Biologie Moléculaire et Cellulaire of the CNRS and Université Louis Pasteur

Affiliations and Expertise

Genomique Moleculaire, Genetique, Microbiologie (GMGM), UMR7156 CNRS – Université de Strasbourg