Long-Range Control of Gene Expression

Long-Range Control of Gene Expression

1st Edition - March 3, 2008

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  • Editors: Veronica van Heyningen, Robert Hill
  • eBook ISBN: 9780080877815

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Description

Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced.

Key Features

  • Discusses the evolution of cis-regulatory sequences in drosophila
  • Includes information on genomic imprinting and imprinting defects in humans
  • Includes a chapter on epigenetic gene regulation in cancer

Readership

Molecular geneticists, clinical geneticists, neurologists, neuroscientists, molecular biologists and biochemists, cell and developmental biologists

Table of Contents

  • Chromatin Structure and the Regulation of Gene Expression: The Lessons of Pev in Drosophila

    Polycomb Group Proteins and Long-Range Gene Regulation

    Evolution of cis-Regulatory Sequences in Drosophila

    Beta Globin Regulation and Long-Range Interactions

    Long-Range Regulation of Ą-globin Gene Expression

    Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution

    Regulation of Imprinting in Clusters: Noncoding RNAs Versus Insulators

    Genomic Imprinting and Imprinting Defects in Humans

    Epigenetic Gene Regulation in Cancer

    Genomic Identification of Regulatory Elements by Evolutionary Sequence Comparison and Functional Analysis

    Regulatory Variation and Evolution and Implications for Disease

    Organization of Conserved Elements Near Key Developmental Regulators in Vertebrate Genomes

    Long-Range Gene Control and Genetic Disease
    Dirk A. Kleinjan and Laura A. Lettice

Product details

  • No. of pages: 416
  • Language: English
  • Copyright: © Academic Press 2008
  • Published: March 3, 2008
  • Imprint: Academic Press
  • eBook ISBN: 9780080877815

About the Editors

Veronica van Heyningen

Affiliations and Expertise

Veronica van Heyningen [v.vanheyningen@hgu.mrc.ac.uk]

Robert Hill

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