Long-Range Control of Gene Expression - 1st Edition - ISBN: 9780123738813, 9780080877815

Long-Range Control of Gene Expression, Volume 61

1st Edition

Editors: Veronica van Heyningen Robert Hill
eBook ISBN: 9780080877815
Hardcover ISBN: 9780123738813
Imprint: Academic Press
Published Date: 3rd March 2008
Page Count: 416
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Table of Contents

Chromatin Structure and the Regulation of Gene Expression: The Lessons of Pev in Drosophila

Polycomb Group Proteins and Long-Range Gene Regulation

Evolution of cis-Regulatory Sequences in Drosophila

Beta Globin Regulation and Long-Range Interactions

Long-Range Regulation of Ą-globin Gene Expression

Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution

Regulation of Imprinting in Clusters: Noncoding RNAs Versus Insulators

Genomic Imprinting and Imprinting Defects in Humans

Epigenetic Gene Regulation in Cancer

Genomic Identification of Regulatory Elements by Evolutionary Sequence Comparison and Functional Analysis

Regulatory Variation and Evolution and Implications for Disease

Organization of Conserved Elements Near Key Developmental Regulators in Vertebrate Genomes

Long-Range Gene Control and Genetic Disease Dirk A. Kleinjan and Laura A. Lettice


Description

Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced.

Key Features

  • Discusses the evolution of cis-regulatory sequences in drosophila
  • Includes information on genomic imprinting and imprinting defects in humans
  • Includes a chapter on epigenetic gene regulation in cancer

Readership

Molecular geneticists, clinical geneticists, neurologists, neuroscientists, molecular biologists and biochemists, cell and developmental biologists


Details

No. of pages:
416
Language:
English
Copyright:
© Academic Press 2008
Published:
Imprint:
Academic Press
eBook ISBN:
9780080877815
Hardcover ISBN:
9780123738813

About the Editors

Veronica van Heyningen Editor

Affiliations and Expertise

Veronica van Heyningen [v.vanheyningen@hgu.mrc.ac.uk]

Robert Hill Editor