Lipidomics and Bioactive Lipids: Specialized Analytical Methods and Lipids in Disease

Lipidomics and Bioactive Lipids: Specialized Analytical Methods and Lipids in Disease

1st Edition - November 9, 2007
This is the Latest Edition
  • Editor: H. Alex Brown
  • eBook ISBN: 9780080560656
  • Hardcover ISBN: 9780123739667

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Description

This volume in the well-established Methods in Enzymology series features methods for the study of lipids using mass spectrometry techniques. Articles in this volume cover topics such as Liquid chromatography mass spectrometry for quantifying plasma lysophospholipids: potential biomarkers for cancer diagnosis; Measurement of eicosanoids in cancer tissues; Noninvasive Assessment of the Role of Cyclooxygenases in Cardiovascular HealthA Detailed HPLC/MS/MS Method; Lipidomics in Diabetes and the Metabolic Syndrome; LC-MS-MS Analysis of Neutral Eicosanoids; Quantification Of F2-Isoprostanes In Biological Fluids And Tissues As A Measure Of Oxidant Stress; Measurement of Products of Docosahexaenoic Acid Peroxidation, Neuroprostanes, and Neurofurans; Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatography; Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS); Shotgun Lipidomics by Tandem Mass Spectrometry under Data-Dependent Acquisition Control; Identification of Intact Lipid Peroxides by Ag+ Coordination Ionspray Mass Spectrometry (CIS-MS); Quantification of Cardiolipin by Liquid Chromatography Electrospray Ionization Mass Spectrometry.

Readership

Graduate students, researchers in academics and industry studying biochemistry.

Table of Contents

  • Chapter 1
    Liquid chromatography mass spectrometry for quantifying plasma lysophospholipids: potential biomarkers for cancer diagnosis
    Mandi Murph, Tamotsu Tanaka, Jihai Pang, Edward Felix, Shuying Liu, Rosanne Trost, Andrew K. Godwin, Robert Newman and Gordon Mills

    Chapter 2
    Measurement of eicosanoids in cancer tissues
    Dingzhi Wang and Raymond N. DuBois

    Chapter 3
    Noninvasive Assessment of the Role of Cyclooxygenases in Cardiovascular Health
    A Detailed HPLC/MS/MS Method
    Wen-Liang Song, John A. Lawson, Helen Zou, and Garret A. FitzGerald

    Chapter 4
    Lipidomics in Diabetes and the Metabolic Syndrome
    Richard W. Gross, Xianlin Han

    Chapter 5
    LC-MS-MS Analysis of Neutral Eicosanoids
    Philip J. Kingsley and Lawrence J. Marnett

    Chapter 6
    Quantification Of F2-Isoprostanes In Biological Fluids And Tissues As A Measure Of Oxidant Stress
    Ginger L. Milne, Huiyong Yin, Joshua D. Brooks, Stephanie Sanchez, L. Jackson Roberts, II, and Jason D. Morrow

    Chapter 7
    Measurement of Products of Docosahexaenoic Acid Peroxidation, Neuroprostanes, and Neurofurans
    Kyle O. Arneson and L. Jackson Roberts, II.

    Chapter 8
    Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatography
    Claus Schneider, Zheyong Yu, William E. Boeglin, Yuxiang Zheng, and Alan R. Brash

    Chapter 9
    Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS)
    Seon Hwa Lee and Ian A. Blair

    Chapter 10
    Shotgun Lipidomics by Tandem Mass Spectrometry under Data-Dependent Acquisition Control
    Dominik Schwudke, Gerhard Liebisch, Ronny Herzog, Gerd Schmitz and Andrej Shevchenko

    Chapter 11
    Identification of Intact Lipid Peroxides by Ag+ Coordination Ionspray Mass Spectrometry (CIS-MS)
    Huiyong Yin and Ned A. Porter

    Chapter 12
    Quantification of Cardiolipin by Liquid Chromatography Electrospray Ionization Mass Spectrometry
    Teresa A. Garrett*, Reza Kordestani, Christian R. H. Raetz

Product details

  • No. of pages: 296
  • Language: English
  • Copyright: © Academic Press 2007
  • Published: November 9, 2007
  • Imprint: Academic Press
  • eBook ISBN: 9780080560656
  • Hardcover ISBN: 9780123739667
  • About the Serial Volume Editor

    H. Alex Brown