
Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates
Description
Key Features
- Highlights the latest developments in the field in a concise volume
- Provides details of key fluorinating reagents across diverse families of organic compounds
- Explores the current applications and future potential of fluorine in drug development
Readership
Medicinal Chemists, Synthetic Chemists, Pharmaceutical Scientists, Drug Discovery Researchers, Academia
Table of Contents
1. Introduction and Highlights
2. 18F radiolabeling of bioactive compounds
3. Electrophilic and oxidative fluorination of aromatic compounds
4. Enantioselective fluorination
5. Visible-Light-Mediated C-F bond Activation
6. Photocatalytic fluorination reactions
7. Fluorination of allylic positions towards the synthesis of fluorinated bioactive compounds
8. Difluoromethylation of Bioactive Compounds
9. Fluorination of Bioactive Compounds by Electron Transfer Reactions
10. Fluorine-Containing Pharmaceuticals and the Phenomenon of Self-Disproportionation of Enantiomers (SDE)
Product details
- No. of pages: 390
- Language: English
- Copyright: © Elsevier 2018
- Published: September 5, 2018
- Imprint: Elsevier
- Paperback ISBN: 9780128129586
- eBook ISBN: 9780128130391
About the Author
Al Postigo
Affiliations and Expertise
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