Laboratory Animal Medicine

Laboratory Animal Medicine

1st Edition - January 1, 1984

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  • Editors: James G. Fox, Bennett J. Cohen, Franklin M. Loew
  • eBook ISBN: 9781483269160

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Description

Laboratory Animal Medicine is a compilation of papers that deals with the diseases and biology of major species of animals used in medical research. The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals. Several papers discuss the biology and diseases of mice, hamsters, guinea pigs, and rabbits. Another paper addresses the dog and cat as laboratory animals, including sourcing of these animals, housing, feeding, and their nutritional needs, as well as breeding and colony management. The book also describes ungulates as laboratory animals, including topics on sourcing, husbandry, preventive medical treatments, and housing facilities. One paper addresses primates as test animals, covering the biology and diseases of old world primates, Cebidae, and ferrets. Some papers pertain to the treatment, diseases, and needed facilities for birds, amphibians, and fish. Other papers then deal with techniques of experimentation, anesthesia, euthanasia, and some factors (spontaneous diseases) that complicate animal research. The text can prove helpful for scientists, clinical assistants, and researchers whose work involves laboratory animals.

Table of Contents


  • List of Contributors

    Preface

    List of Reviewers for Chapters in This Volume

    Chapter 1 Laboratory Animal Medicine: Historical Perspectives

    I. Introduction

    II. Origins of Animal Experimentation

    III. Early Veterinarians in Laboratory Animal Science and Medicine

    IV. The Organizations of Laboratory Animal Science

    V. Education and Training in Laboratory Animal Medicine

    VI. Impact of Laws, Regulations, and Guidelines on Laboratory Animal Medicine

    VII. Regulation of Animal Research in the United Kingdom and Canada

    VIII. Commercial Rodent Breeding IX. Conclusion

    References

    Chapter 2 Laws, Regulations, and Policies Affecting the Use of Laboratory Animals

    I. Introduction

    II. Animal Welfare

    III. Collection, Importation, Exportation, and Shipment of Animals

    IV. Hazardous Substances

    V. Good Laboratory Practices

    References

    Chapter 3 Biology and Diseases of Mice

    I. Introduction

    II. Biology

    III. Diseases

    References

    Chapter 4 Biology and Diseases of Rats

    I. Introduction

    II. Biology

    III. Diseases

    References

    Chapter 5 Biology and Diseases of Hamsters

    Syrian Hamster

    I. Introduction

    II. Biology

    III. Diseases

    Chinese Hamster

    I. Introduction

    II. Biology

    III. Diseases

    European Hamster

    I. Introduction

    II. Biology

    III. Diseases

    Armenian Hamster

    References

    Chapter 6 Biology and Diseases of Guinea Pigs

    I. Introduction

    II. Biology

    III. Diseases

    References

    Chapter 7 Biology and Diseases of Other Rodents

    I. Introduction

    II. Biology

    III. Diseases

    References

    Chapter 8 Biology and Diseases of Rabbits

    I. Introduction

    II. Biology

    III. Diseases

    References

    Chapter 9 Dogs and Cats as Laboratory Animals

    I. Introduction

    II. Types and Sources of Dogs and Cats

    III. Housing

    IV. Conditioning

    V. Canine and Feline Breeding Colony Management

    VI. Nutrition and Feeding

    VII. Diseases

    VIII. Selected Normative Data

    References

    Chapter 10 Ungulates as Laboratory Animals

    I. Introduction

    II. Taxonomy

    III. General Comments and Examples of Use in Research

    IV. Availability, Sources, and Acquisition

    V. Evaluation of Incoming Animals

    VI. Routine Health Maintenance

    VII. Synchronization of Ovulation

    VIII. Facilities

    IX. Appendix

    References

    Chapter 11 Primates

    Introduction

    References

    Part A. Biology and Diseases of Old World Primates

    I. Research Considerations

    II. Biology

    III. Diseases

    References

    Part B. Biology and Diseases of Cebidae

    I. Research Considerations

    II. Generic Profiles and Biological Characteristics

    III. Diseases

    References

    Part C. Biology and Diseases of Callitrichidae

    I. Research Considerations

    II. Biology

    III. Diseases

    References

    Chapter 12 Biology and Diseases of Ferrets

    I. Introduction

    II. Biology

    III. Routine Veterinary Medical Care

    IV. Infectious Diseases

    V. Nutritional and Metabolic Diseases

    VI. Neoplastic Diseases

    References

    Chapter 13 Biology and Diseases of Birds

    I. Introduction

    II. Biology

    III. Diseases Caused by Bacteria

    IV. Diseases Caused by Viruses

    V. Diseases Caused by Parasites

    VI. Diseases Caused by Fungi/Yeasts

    VII. Diseases Resulting in Neoplastic Changes

    VIII. Diseases Caused by Nutritional Deficiencies

    Selected References

    Chapter 14 Biology and Diseases of Amphibians

    I. Introduction

    II. Biology

    III. Diseases

    References

    Chapter 15 Biology and Diseases of Reptiles

    I. Introduction

    II. Biology

    III. Diseases

    References

    Chapter 16 Biology and Diseases of Fish

    I. Introduction

    II. Biology

    III. Diseases

    References

    Chapter 17 Design and Management of Animal Facilities

    I. Introduction

    II. Facilities Design and Equipment

    III. Management

    IV. Conclusion

    References

    Chapter 18 Preanesthesia, Anesthesia, Analgesia, and Euthanasia

    I. Introduction

    II. Preanesthesia, Anesthesia, and Analgesia

    III. Euthanasia

    References

    Chapter 19 Techniques of Experimentation

    I. Introduction

    II. Identification Methods

    III. Blood Collection and Intravenous Injection

    IV. Vascular Cannulation

    V. Intraperitoneal Injection

    VI. Subcutaneous and Intramuscular Injection

    VII. Oral Administration of Substances

    VIII. Digestive System

    IX. Urinary Techniques

    X. Respiratory System Techniques

    XI. Reproductive System

    XII. Cardiovascular Techniques

    XIII. Endocrine System Techniques

    XIV. Orthopedic Procedures for Laboratory Animals

    XV. Neurosurgical Techniques

    XVI. Tumor Transplantation

    References

    Chapter 20 Control of Biohazards Associated with the Use of Experimental Animals

    I. Introduction

    II. The Infectious Process

    III. Risk Assessment

    IV. Biosafety Practices and Procedures

    V. Summation

    References

    Chapter 21 Genetic Monitoring

    I. Introduction

    II. Sources of Genetic Impurity of Inbred Strains

    III. Evidence of Genetic Contamination

    IV. Methods of Genetic Monitoring

    V. Summary

    References

    Chapter 22 Selected Zoonoses and Other Health Hazards

    I. Introduction

    II. Viral Diseases

    III. Rickettsial and Chlamydial Diseases

    IV. Bacterial Diseases

    V. Mycoses

    VI. Protozoan Diseases

    VII. Helminth Infections

    VIII. Arthropod Infestations

    IX. Bites and Scratches

    X. Allergic Sensitivities

    XI. Conclusions

    References

    Chapter 23 Factors That Complicate Animal Research

    I. Introduction

    II. Physical Factors

    III. Chemical Factors

    IV. Microbial Factors

    References

    Chapter 24 Animal Models in Biomedical Research

    I. Introduction

    II. History

    III. Symposia

    IV. Publications

    V. Selection of Animals

    VI. Selected Animal Models

    References

    Additional Books, Proceedings, and Bulletins

    Chapter 25 Developing Research in Laboratory Animal/Comparative Medicine

    I. Introduction

    II. The Research Process

    III. Training for Research in Laboratory

    IV. Animal/Comparative Medicine

    V. Development of Research Resources

    VI. Support for Research

    References

    Chapter 26 Rodent and Lagomorph Health Surveillance—Quality Assurance

    I. Introduction

    II. Design of Quality Assurance Programs

    III. Quarantine

    IV. Conclusions

    References

    Index


Product details

  • No. of pages: 766
  • Language: English
  • Copyright: © Academic Press 1984
  • Published: January 1, 1984
  • Imprint: Academic Press
  • eBook ISBN: 9781483269160

About the Editors

James G. Fox

Bennett J. Cohen

Franklin M. Loew

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