
Laboratory Animal Medicine
Description
Key Features
- Organized by species for in-depth understanding of biology, health, and best care of animals
- Features the inclusion of chinchillas, quail, and zebra finches as animal models
- Offers guidance on program and employee management
- Covers regulations, policies, and laws for laboratory animal management worldwide
Readership
Table of Contents
- List of Reviewers
- List of Contributors
- Preface to the Third Edition
- Chapter 1. Laboratory Animal Medicine: Historical Perspectives
- I Introduction
- II Origins of Animal Experimentation
- III Early Veterinarians in Laboratory Animal Science and Medicine
- IV The Organizations of Laboratory Animal science
- V Education and Training in Laboratory Animal Medicine
- VI ACLAM-Sponsored Texts
- VII Impact of Laws, Regulations, and Guidelines on Laboratory Animal Medicine
- VIII Regulation of Animal Research in the United Kingdom and Canada
- IX Commercial and Academic Breeding of Rodents
- X Conclusion
- Acknowledgment
- References
- Chapter 2. Laws, Regulations, and Policies Affecting the Use of Laboratory Animals
- I Introduction
- II Animal Welfare
- III Importation and Exportation of Animals and Animal Products
- IV Hazardous Substances
- V Nucleic Acid and Nanomaterial Research Guidelines
- References
- Chapter 3. Biology and Diseases of Mice
- I Introduction
- II Biology
- III Diseases
- References
- Chapter 4. Biology and Diseases of Rats
- I Introduction
- II Biology
- III Diseases
- Acknowledgment
- References
- Chapter 5. Biology and Diseases of Hamsters
- I Introduction
- II Syrian Hamster
- III Chinese Hamster
- IV Armenian Hamster
- V European Hamster
- VI Djungarian Hamster
- References
- Chapter 6. Biology and Diseases of Guinea Pigs
- I Introduction
- II Biology
- III Diseases
- References
- Chapter 7. Biology and Diseases of Other Rodents
- I Introduction
- II Ground Squirrels: Urocitellus, Ictodomys, and Spermophilus
- III Prairie Dogs: Cynomys
- IV Pocket Gophers: Geomyidae
- V Kangaroo Rats: Dipodomys
- VI Pack Rats: Neotoma
- VII Grasshopper Mice: Onychomys
- VIII Deer Mice: Peromyscus
- IX Rice Rats: Oryzomys
- X Cane Mice: Zygodontomys
- XI Cotton Rats: Sigmodon
- XII White-Tailed Rats: Mystromys
- XIII Gerbils and Jirds: Meriones
- XIV Voles: Microtus
- XV Multimammate Rats/Mice: Mastomys
- XVI Degus: Octodon
- XVII Naked Mole Rats: Heterocephalus Glaber
- References
- Chapter 8. The Laboratory Woodchuck (Marmota monax)
- I Introduction
- II Biology
- III Diseases
- IV The Woodchuck as an Experimental Animal Model for HBV Research
- References
- Chapter 9. Biology and Diseases of Chinchillas
- I Introduction
- II Biology
- III Diseases
- References
- Chapter 10. Biology and Diseases of Rabbits
- I Introduction
- II Biology
- III Diseases
- References
- Chapter 11. Microbiological Quality Control for Laboratory Rodents and Lagomorphs
- I Introduction
- II Microbiological Quality Specifications
- III Biosecurity
- IV Health Monitoring
- V Outbreak Management and Investigation
- References
- Chapter 12. Biology and Diseases of Dogs
- I Introduction
- II Biology
- III Diseases
- Acknowledgments
- References
- Chapter 13. Biology and Diseases of Cats
- I Introduction
- II Sources of Cats
- III Housing
- IV Breeding Colony Management
- V Nutrition and Feeding
- VI Infectious Disease Exclusion and Control
- Acknowledgments
- References
- Chapter 14. Biology and Diseases of Ferrets
- I Introduction
- II Biology
- III Diseases
- Acknowledgment
- References
- Chapter 15. Biology and Diseases of Ruminants (Sheep, Goats, and Cattle)
- I Introduction
- II Biology
- III Diseases
- References
- Chapter 16. Biology and Diseases of Swine
- I Introduction
- II Biology
- III Diseases
- Acronyms Used in Chapter
- Acknowledgments
- References
- Chapter 17. Nonhuman Primates
- I Introduction
- II Taxonomy
- III Biology
- IV Principles of Colony Management
- V Medical Management
- VI Diseases
- Acknowledgments
- References
- Chapter 18. Biology and Diseases of Amphibians
- I Introduction
- II Biology
- III Diseases
- References
- Chapter 19. Biology and Diseases of Reptiles
- I Introduction
- II Biology
- III Diseases
- References
- Chapter 20. The Biology and Management of the Zebrafish
- I Introduction
- II Zebrafish: The Experimental Model in Biomedical Research
- III Significances of Healthy Management in the Aquatic Animal Facility
- IV Environmental Factors Important to Zebrafish Health
- V General Features of Laboratory Zebrafish Facilities
- VI Nutrition and Feeding of Zebrafish
- VII Pathogen Control Program
- VIII Techniques and Anesthesia
- IX Significant Diseases of Laboratory Zebrafish
- Acknowledgment
- References
- Chapter 21. Biology and Management of Laboratory Fishes
- I Introduction
- II Facility Design
- III Management and Husbandry
- IV Medical Protocols
- V Zoonotic Considerations
- VI Diseases
- References
- Chapter 22. Japanese Quail as a Laboratory Animal Model
- I Introduction
- II Biology
- III Laboratory Management and Husbandry
- IV Breeding and Rearing Quail
- V Diseases/Welfare Concerns
- References
- Chapter 23. Zebra Finches in Biomedical Research
- I Introduction
- II History and Taxonomy
- III Research Uses
- IV Biology
- V Laboratory Management and Husbandry
- VI Diseases/Welfare Concerns
- References
- Chapter 24. Preanesthesia, Anesthesia, Analgesia, and Euthanasia
- I Introduction
- II Rodents
- III Rabbits
- IV Ferrets
- V Swine
- VI Small Ruminants
- VII Nonhuman Primates
- References
- Chapter 25. Techniques of Experimentation
- I Introduction
- II Identification Methods
- III Blood Collection and Intravenous Injection
- IV Vascular Cannulation
- V Intraperitoneal Injection
- VI Subcutaneous, Intramuscular, and Intraosseous Injection
- VII Digestive System
- VIII Urinary System Techniques
- IX Respiratory System Techniques
- X Reproductive System
- XI Cardiovascular Techniques
- XII Endocrine System Techniques
- XIII Orthopedic Procedures for Laboratory Animals
- XIV Neurosurgical Techniques
- XV Tumor Transplantation
- XVI Imaging Techniques
- XVII Radiotelemetry
- XVIII Thymectomy
- Acknowledgments
- References
- Chapter 26. Gnotobiotics
- I Introduction
- II Terminology
- III History
- IV Characteristics of Gnotobiotes
- V Establishing a Gnotobiotic Facility
- VI Operation
- VII Derivation of Germfree Mice
- VIII. Resources
- References
- Chapter 27. Working Safely with Experimental Animals Exposed to Biohazards
- I Introduction
- II Risk Assessment
- III Managing an Animal Biocontainment Program
- IV Standard Practices
- V Veterinary Care
- VI Other Considerations
- VII Summary
- References
- Chapter 28. Selected Zoonoses
- I Introduction
- II Viral Diseases
- III Rickettsial Diseases
- IV Chlamydial Infections
- V Bacterial Diseases
- VI Fungal Diseases
- VII Protozoal Diseases
- VIII Helminth Infections
- IX Arthropod Infestations
- Acknowledgments
- References
- Chapter 29. Xenozoonoses: The Risk of Infection after Xenotransplantation
- I Introduction
- II Lessons from Allotransplantation/Historical Perspective
- III Potential Mechanisms for Cross-Species Infections
- IV NonViral Agents
- V Development of SPF Herds
- VI Potential Benefits of Xenotransplantation and Other Infectious Disease Issues
- VII Issues after Xenotransplantation
- References
- Chapter 30. Occupational Health of Laboratory Animal Workers
- I Introduction
- II Occupational Illness and Injury in Laboratory Animal Workers
- III Occupational Health Approach
- IV Hazard Identification
- V Hazard Controls
- VI Occupational Medicine Services
- Appendix 30.1
- Appendix 30.2
- References
- Chapter 31. Genetic Monitoring of Laboratory Mice and Rats
- I Introduction
- II History of Genetic Monitoring
- III Rodent Strains: Genetic Homogeneity or Genetic Diversity
- IV SNP Analysis: Testing Strain Background
- V Allele-Specific Genotyping: Testing Mutant Strains
- VI Maintaining Strains
- VII Phenotype Quality Control
- VIII The Future of GQC
- IX GQC: Practical Aspects
- X Conclusions
- References
- Chapter 32. Genetically Modified Animals
- I Introduction
- II Manipulating Animals for Genetic Modification
- III Genetic Modification and Technologies
- IV Colony Management for GM Mice and Rats
- V Finding Mouse and Rat Resources
- References
- Chapter 33. Factors That Can Influence Animal Research
- I Introduction
- II Intrinsic Considerations
- III Extrinsic Considerations
- References
- Chapter 34. Animal Models in Biomedical Research
- I Introduction
- II What is an Animal Model?
- III Nature of Research
- IV History of Animal Use in Biomedical Research
- References
- Chapter 35. Research in Laboratory Animal and Comparative Medicine
- I Introduction
- II Principles of Experimentation
- III Role of the Laboratory Animal Specialist in Research
- IV Research Training
- V Summary
- Acknowledgment
- References
- Chapter 36. Design and Management of Research Facilities
- I Introduction
- II Facility Planning and Design
- III Environmental Control and Monitoring
- IV Housing and Equipment
- V Materials
- VI Operational Issues
- VII Conclusions
- References
- Chapter 37. Program Management
- I Introduction and Definitions
- II Mission and Strategy: Where it All Starts
- III Managing People
- IV Managing Money
- V Managing Operations
- VI Concluding Remarks
- Appendix 1 Executive Summary of the 14 Toyota Way Principles (Reprinted with Permission, McGraw-Hill Education Holdings, LLC, Philadelphia, PA)
- References
- Chapter 38. Laboratory Animal Behavior
- I Introduction
- II Rodents
- III Rabbits
- IV Laboratory Dogs and Cats
- V Nonhuman Primates
- VI Farm Animals
- VII Conclusions
- References
- Chapter 39. Animal Welfare
- I Introduction
- II Animal Welfare as a Key Component in Research, Teaching, and Testing Using Animals
- III Animal Welfare – A Historical and Philosophical Perspective
- IV Guidelines and Principles
- V Strategies to Optimize Animal Welfare
- VI Examples of Challenging Research and Opportunities for Animal Welfare Optimization
- VII Science of Animal Welfare
- VIII Conclusion and Summary
- References
- Index
Product details
- No. of pages: 1746
- Language: English
- Copyright: © Academic Press 2015
- Published: July 4, 2015
- Imprint: Academic Press
- eBook ISBN: 9780124166134
- Hardcover ISBN: 9780124095274
About the Editor in Chief
James Fox
Affiliations and Expertise
About the Editors
Lynn Anderson
Affiliations and Expertise
Glen Otto
Affiliations and Expertise
Kathleen Pritchett-Corning
Affiliations and Expertise
Mark Whary
Affiliations and Expertise
Ratings and Reviews
Latest reviews
(Total rating for all reviews)
DelphineGrezel Mon Sep 10 2018
Laboratory Animal Medicine
This is clearly a reference book for laboratory animal lovers, veterinarians or scientists as well. This is very complete and up to date, not only on mouse but even less known animals. I appreciate mostly the fact that each assertion is back up by a reference, so you can check if it is relevant or not.