Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals’ body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments.
The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals.
New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area Provides rapid, easily accessed information using tabulated summaries Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely Provides sufficient depth for the more experienced anesthetist moving to this field
Researchers, post docs and graduate students who utilize animals in biomedical research.
Preface Preface to the Second Edition Preface to the First Edition Glossary List of Tables List of Figures Acknowledgements Introduction 1 Preparing for Anaesthesia Anaesthetic equipment and anaesthetic drugs Other equipment Personnel The animal 2 Anaesthesia General anaesthesia 3 Anaesthetic Management Pre-operative preparations Monitoring anaesthesia Anaesthetic problems and emergencies 4 Special Techniques Use of neuromuscular blocking agents Controlled ventilation Long-term anaesthesia Anaesthesia of pregnant animals Anaesthesia of neonates Anaesthesia for imaging 5 Analgesia and Post-operative Care The recovery room environment Problems during the recovery period Management of post-operative pain Pain assessment Pain relief Conclusions 6 Anaesthesia of Common Laboratory Species: Special Considerations Small rodents Rabbits Cats Dogs Ferrets Pigs Sheep and goats Primates Other species Bibliography Appendix 1 Recommended Techniques and Physiological Data Appendix 2 Estimation of Required Quantities of Volatile Anaesthetics and Anaesthetic Gases Appendix 3 Examples of Dilutions of Anaesthetic Mixtures for Small Rodents Appendix 4 Manufacturers of Equipment and Other Items Illustrated or Cited in the Text Index
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- © Academic Press 2009
- 27th May 2009
- Academic Press
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Paul Flecknell is a veterinarian with over 35 years of experience working with laboratory animals. He is a Diplomate of the European Colleges of Veterinary Anaesthesia and Analgesia and Laboratory Animal Medicine and an honorary Diplomate of the American College of Laboratory Animal Medicine. He has PhD in physiology, and is currently Professor of Laboratory Animal Science in the Institute of Neuroscience at Newcastle University. His main research interests are anaesthesia and analgesia of all species of animals and in particular the development of methods of pain assessment. He is the head of the Pain and Animal Welfare Science (PAWS) group at Newcastle. The group’s current research work is focussed on novel methods of “cage-side” assessment of pain, particularly using “pain faces” and developing methods of measurement of affective state in rodents.
Comparative Biology Centre, The Medical School, Newcastle-Upon-Tyne, UK