Molecular Structure

1st Edition - January 28, 1975

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  • Editor: Clement Markert
  • eBook ISBN: 9780323142106

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Isozymes, I: Molecular Structure contains manuscripts presented at the Third International Conference on isozymes convened in April 1974 at Yale University. Separating 52 manuscripts into chapters, this book discusses the biology and biochemistry of isozymes. It also elucidates the multiple forms of mammalian DNA-dependent DNA polymerases, as well as RNA polymerases of maize, fungi, and Escherichia coli. Significant topics on some specific isozymes are given separately in other chapters.

Table of Contents

  • Organizing Committee

    List of Contributors



    Biology of Isozymes

    Biochemistry of Isozymes

    Multiple Forms of Mammalian DNA-Dependent DNA Polymerases

    The RNA Polymerases of the Nucleus and Chloroplasts of Maize

    The RNA Polymerases of Fungi. Glutarimides and the Regulation of RNA Polymerase I.

    RNA Polymerase II of Escherichia coli

    The Role of Subunit Interactions in the Genesis of Non-binomial Lactate Dehydrogenase Isozyme Distributions

    Subunit Interaction in Lactate Dehydrogenase

    A Structural Comparison of Porcine B4 and Dogfish A4 Isozymes of Lactate Dehydrogenase

    The Two-Stage Reversible Denaturation of Lactate Dehydrogenase at Low pH

    Mechanism of Isozyme Formation as Related to Subunit Interactions

    Biochemical and Genetic Studies of Peroxisomal Multiple Enzyme Systems: α-Hydroxyacid Oxidase and Catalase

    Studies on the Electrophoretic Variants of Human Hypoxanthine-Guanine Phosphoribosyltransferase

    Heterogeneity of Human Erythrocyte Catalase

    Affinity Chromatography Resolution of Plasminogen Isozymes

    Multiple Molecular Forms of Transglutaminases in Human and Guinea Pig

    The Isozymes of Two Human Adipose Tissue Lipolytic Activities

    New Chromatographie Approaches to the Separation of Human Alkaline Phosphatase Isozymes

    Alkaline Phosphatase Isozymes in the Alimentary Canal of the Silkworm

    Differences in the Structure, Function, and Formation of Two Isozymes of Escherichia coli Alkaline Phosphatase

    Hormonally Induced Modification of HeLa Alkaline Phosphatase with Increased Catalytic Activity

    Genetic and Non-genetic Variation of Human Acid Phosphatases

    Phosphoglucomutase Isozymes Caused by Sulfhydryl Oxidation

    Carboxylesterase Isozymes in the Rabbit Liver: Physicochemical Properties

    Structural Classes of Jackbean Urease Variants and Their Relation to a Structural Classification of Isozymes

    Rat Liver Tyrosine Aminotransferase: Problems of Interpreting Changes in Multiple Form Patterns

    Molecular Forms of Hepatic Tyrosine Aminotransferase Activity

    The Different Origins of Multiple Molecular Forms of Phosphoglucose Isomerase

    Nature of the Multiple Forms of Glucosephosphate and Triosephosphate Isomerases

    The Use of Thiol Reagents in the Analysis of Isozyme Patterns

    Sulfhydryl Oxidation and Multiple Forms of Human Erythrocyte Pyruvate Kinase

    Bovine and Chicken Pyruvate Kinase Isozymes Intraspecies and Interspecies Hybrids

    Properties of Rat Pyruvate Kinase Isozymes

    Multiple Molecular Forms of Neurospora Mitochondrial Malate Dehydrogenase

    Structural Relationship of Human Erythrocyte Carbonic Anhydrase Isozymes B and C

    Multiplicity of Isozymes of Lipoamide Dehydrogenase and Phospholipase A

    Properties of Multiple Molecular Forms of Lipoamide Dehydrogenase

    Multiple Forms of ß-Glucuronidase: Molecular Nature, Transformation, and Subcellular Translocation

    Gel Isoelectric Focusing and the Microheterogeneity of Human Glucose-6-Phosphate Dehydrogenase

    Investigations on the Quaternary Structure and Function of Oligomeric Proteins by Hybridization with Variants Produced by Chemical Modification

    Radiochemical Assay of Electrophoretically Separated Phosphotransferases Using Lanthanum Precipitation

    Presence of a Diphosphoglycerate Phosphatase Activity in the Multiple Molecular Forms of 3-Phosphoglycerate Mutase

    Heterogeneity, Polymorphism, and Substrate Specificity of Alcohol Dehydrogenase from Horse Liver

    Drosophila Alcohol Dehydrogenase: Origin of the Multiple Forms

    Multiple Molecular Forms of Pneumococcal Neuraminidase

    Isozymes of the Pentose Phosphate Pathway

    Post-Translational Alterations of Human Erythrocyte Enzymes

    A New Purification Procedure for Pig Heart Fumarase

    Multiple Forms of Pig Heart and Herellea vaginicola Succinate Thiokinase, Effects of Sulfhydral Groups and Ligands

    Subtilisin-Like Isozyme in Pronase

    Implications of Macromolecule-Small Molecule Interactions and Kinetically Controlled Reactions for Separation of Proteins by Mass Transport


Product details

  • No. of pages: 876
  • Language: English
  • Copyright: © Academic Press 1975
  • Published: January 28, 1975
  • Imprint: Academic Press
  • eBook ISBN: 9780323142106

About the Editor

Clement Markert

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