Isoenzymes In Biology and Medicine

1st Edition - January 1, 1968
Author: Albert Latner
Language: English
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 1 5 6 9 4 - 3

Isoenzymes in Biology and Medicine attempts to give an account of the study of isoenzymes in relation to humans, animals, insects, higher plants, fungi, protozoa, algae, and… Read more

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Isoenzymes in Biology and Medicine attempts to give an account of the study of isoenzymes in relation to humans, animals, insects, higher plants, fungi, protozoa, algae, and bacteria. This book discusses the chemical structure, physiological aspects, metabolic role, and function of isoenzyme observations in genetic, ontogenic, and phylogenic studies. A detailed account of the use of isoenzyme in the diagnosis and pathogenesis of disease and control of therapy is also provided. This text likewise considers the isoenzymes of the oxidoreductases, transferases, and hydrolases, including its relation to clinical medicine. This publication is intended for biochemists, biologists, clinical biochemists and physicians.

PrefaceAcknowledgmentsI. IntroductionII. Isoenzymes of the Oxidoreductases 1. Lactate Dehydrogenase 2. Malate Dehydrogenase 3. Isocitrate Dehydrogenase 4. Galactose Dehydrogenase 5. Glutamate Dehydrogenase 6. Glucose-6-Phosphate Dehydrogenase 7. Phosphogluconate Dehydrogenase 8. Alcohol Dehydrogenase 9. Catalase 10. Multiple Dehydrogenase ActivitiesIII. Isoenzymes of the Transferases 1. Aspartate Aminotransferase 2. Hexokinase 3. Creatine Kinase 4. Pyruvate Kinase 5. Carbonic AnhydraseIV. Isoenzymes of the Hydrolases 1. Non-Specific Alkaline Phosphatase 2. Specific Alkaline Phosphatases 3. Acid phosphatase 4. Esterases 5. Arylamidase 6. Amylase 7. Glutaminase 8. Miscellaneous Enzymes 9. AldolaseV. Phsiological Aspects and Metabolic Role 1. Lactate Dehydrogenase 2. Malate Dehydrogenase 3. Aspartate Kinase 4. Aminotransferases 5. Creatine Kinase 6. Hexokinase 7. Hydrolases 8. Other Enzyme SystemsVI. Genetic Studies 1. Lactate Dehydrogenase 2. Isocitrate Dehydrogenase 3. Phosphogluconate Dehydrogenase 4. Glucose-6-Phosphate Dehydrogenase 5. Adenylate Kinase 6. Phosphoglucomutase 7. Esterases 8. Alkaline Phosphatase 9. Acid Phosphatase 10. Amylase 11. Leucine AminopeptidaseVII. Ontogenic and Phylogenic Studies 1. Ontogeny 2. Evolutionary and Phylogenic StudiesVIII. Insects, Plants and Lower Organisms 1. Insects 2. Higher Plants 3. Fungi 4. Protozoa 5. Algae 6. BacteriaIX. Isoenzymes in Relation to Clinical Medicine 1. Lactate Dehydrogenase 2. Aspartate Aminotransferase 3. Creatine Phosphotransferase 4. Alkaline Phosphatase 5. Acid Phosphatase 6. Arylamidase 7. Esterases 8. Isoenzymes, in CancerX. Technical Methods 1. Separation Techniques 2. Methods of Demonstrating Enzyme Activity 3. Immunological TechniquesReferencesAppendixAuthor IndexSubject Index