Environmental Causes and Prevention Measures for Alzheimer’s Disease - 1st Edition - ISBN: 9780128111628, 9780128111635

Environmental Causes and Prevention Measures for Alzheimer’s Disease

1st Edition

Authors: George Brewer
eBook ISBN: 9780128111635
Paperback ISBN: 9780128111628
Imprint: Academic Press
Published Date: 27th September 2017
Page Count: 154
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Environmental Causes and Prevention Measures for Alzheimer’s Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers.

Key Features

  • Emphasizes the history and epidemiology of Alzheimer’s disease, highlighting its epidemic proportions in developed countries
  • Discusses data on new environmental factors in developed countries
  • Provides prevention measures to potentially reduce Alzheimer’s rates through diet


Neuroscientists, medical professionals in neuroscience and neurology, toxicologists, biological scientists, epidemiologists, postdoctoral fellows, and graduate students

Table of Contents

1. Introduction
2. A Little Background on Dementia and Alzheimer's Disease
3. Interesting and Important Historical and Demographic Facts About the Epidemic of Alzheimer's Disease Pointing to Environmental Intoxicants Causing the Epidemic
4. Candidate Environmental Factors for the Alzheimer's Epidemic Part 1: The Metals - Aluminum, Lead, Mercury, Zinc, Iron, and Copper
5. Candidate Environmental Factors for the Alzheimer's Epidemic Part 2: Diet and Other Life Style Factors
6. Identification of Copper-2, and Copper in General as Major Environmental Intoxicants in the Alzheimer’s Epidemic: The Copper Hypothesis
7. Background on Copper, Including Why Copper-2 is so Specifically Neurotoxic
8. Inorganic Copper, or Copper-2, Ingestion as a Major Causal Factor for Alzheimer's Disease - The Web of Evidence
9. Increased Copper Absorption Resulting from Dietary Changes in Developed Countries as Another Causal Factor in the Alzheimer’s Disease Epidemic
10. The Copper Hypothesis Fits Nicely with Known Risk Factors and Theories of Alzheimer’s Disease Causation
11. Prevention Measures Action Items: Two Simple Steps to Eliminate Ingestion of Copper-2, and Dietary Changes to Reduce Copper Absorption
12. Failures: What the Government Hasn't Done to Ensure Healthy Drinking Water and Nontoxic Multimineral/Multivitamin Pills
13. Treatment of Alzheimer’s Disease
14. Summary and Conclusions



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About the Author

George Brewer

Dr. Brewer has a bachelor’s degree in pharmacy and a medical degree. After completing his internship, fellowship and residency at the University of Chicago, he accepted a position at the NIH at Michigan’s Department of Human Genetics in 1963. He became an assistant professor of internal medicine and then full professor in five years, in the Departments of Human Genetics and Internal Medicine. He also was an adjunct professor of veterinary medicine at nearby Michigan State University from 1989 to 1995. During this time, Dr. Brewer developed zinc as a therapy for Wilson’s disease and received U.S. FDA approval. He is currently developing a drug for multiple therapeutic purposes. He has held memberships in more than 15 professional societies, serving as president of the regional chapter of the American Federation of Clinical Research, the American College of Nutrition and the International Society for Trace Elements Research in Humans. He has authored 342 publications and received numerous awards including the Distinguished Alumni Award from the University of Chicago, the Raulin Award from the International Society for Trace Element Research in Humans, and the Master Award from the American College of Nutrition. He is a Fellow in the American Association for the Advancement of Science.

Affiliations and Expertise

Morton S. and Henrietta K. Sellner Emeritus Professor of Human Genetics and Emeritus Professor of Internal Medicine, Retired, University of Michigan, Ann Arbor, MI, USA

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