The Complex Connection between Cannabis and Schizophrenia

The Complex Connection between Cannabis and Schizophrenia

1st Edition - August 25, 2017
This is the Latest Edition
  • Editors: Michael Compton, Marc Manseau
  • Paperback ISBN: 9780128047910
  • eBook ISBN: 9780128051832

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Description

The Complex Connection between Cannabis and Schizophrenia provides an in-depth overview of the current state of research into the role that cannabis plays in schizophrenia, covering both the pathophysiological and the pharmacological implications. It addresses the epidemiology of cannabis use and the risks associated with its use, the biological aspects of the drug, its effects on the brain and the pharmacological possibilities of using cannabidiol to treat schizophrenia. It is the only book on the market devoted exclusively to examining the links between this very commonly used (and misused) drug and a specific set of devastating psychiatric illnesses, providing a comprehensive guide to our current understandings of this relationship. Marijuana is the most commonly used illicit drug globally, and is becoming increasingly decriminalized and even legalized worldwide. Among the numerous mental-health concerns related to the drug, there is mounting evidence of an intricate link between cannabis use and schizophrenia and related psychotic disorders. At the same time, there is promising evidence to suggest that cannabidiol, one of the many compounds found in cannabis that activates the brain’s cannabinoid receptors, could prove to be an effective antipsychotic to treat schizophrenia.

Key Features

  • Synthesizes existing knowledge about the confusing, but crucial, relationship between cannabis use and schizophrenia symptoms
  • Provides a comprehensive overview of the neurobiological mechanisms of cannabis use and its effects on the brain, including an exploration of the endocannabinoid system
  • Examines the promising evidence suggesting cannabidiol as an effective antipsychotic treatment for schizophrenia
  • Aids readers studying the neurobiological underpinning of cannabis addiction and psychosis in determining directions for their own future research

Readership

Researchers and advanced students in behavioral neuroscience, translational neuroscience, neuropharmacology, neurological disorders, psychopathology, and addiction

Table of Contents

  • 1. Introduction to the Complex Connection between Cannabis Use and Psychosis, Psychotic Disorders, and Schizophrenia
    Marc W. Manseau and Michael T. Compton
    2. The Epidemiology of Cannabis Use in the United States
    Wilson M. Compton and Beth Han
    3. The Biology of Cannabis in the Brain, and the Endocannabinoid System
    David Louis Atkinson and Jeff. K. Abbott
    4. Psychotomimetic and Cognitive Effects of Δ9-Tetrahydrocannabinol in Laboratory Settings
    John D. Cahill, Swapnil Gupta, Jose Cortes-Briones, Rajiv Radhakrishnan, Mohamed Sherif, Deepak C. D'Souza
    5. Psychotomimetic and Cognitive Effects of Cannabis Use in the General Population
    Nadia Solowij
    6. Effects of Cannabis Use among those with Schizotypy
    Angelo B. Cedeno
    7. Effects of Cannabis Use among those at Clinical High Risk for Schizophrenia
    Brian O'Donoghue, Meredith McHugh, Barnaby Nelson, and Patrick McGorry
    8. Cannabis-Induced Psychotic Disorders
    Luca Pauselli
    9. Synthetic Cannabinoids and Synthetic Cannabinoid-Induced Psychotic Disorders
    Papanti Duccio, Schifano Fabrizio, and Orsolini Laura
    10. Cannabis Use as an Independent Risk Factor for, or Component Cause of, Schizophrenia and Related Psychotic Disorders
    Jodi M. Gilman, Sara M. Sobolewski, and Anne Eden Evins
    11. Cannabis Use as a Determinant of Earlier Age at Onset of Schizophrenia and Related Psychotic Disorders
    Claire Ransay Wan and Beth Broussard
    12. The Prevalence of Cannabis Use, and Effects on Course and Outcomes, among Individuals with Schizophrenia and Related Psychotic Disorders
    Ana Fresán, Rebeca Robles-García, and Carlos-Alfonso Tovilla-Zarate
    13. The Treatment of Cannabis Use Disorders among Individuals with Psychotic Disorders
    Peter Bosanac, Ana Lusicic, and David J. Castle
    14. Cannabidiol as a Potential Novel Therapeutic Agent for Psychotic Disorders
    Serena Deiana and Erica Zamberletti

Product details

  • No. of pages: 362
  • Language: English
  • Copyright: © Academic Press 2017
  • Published: August 25, 2017
  • Imprint: Academic Press
  • Paperback ISBN: 9780128047910
  • eBook ISBN: 9780128051832
  • About the Editors

    Michael Compton

    Professor of Clinical Psychiatry, Columbia University College of Physicians and Surgeons, NY, USA

    Affiliations and Expertise

    Professor of Clinical Psychiatry, Columbia University College of Physicians and Surgeons, NY, USA

    Marc Manseau

    Clinical Assistant Professor of Psychiatry, New York University School of Medicine, NY USA

    Affiliations and Expertise

    Clinical Assistant Professor of Psychiatry, New York University School of Medicine, NY USA