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The Neuroscience of Cocaine - 1st Edition - ISBN: 9780128037508, 9780128037928

The Neuroscience of Cocaine

1st Edition

Mechanisms and Treatment

Editor: Victor Preedy
Hardcover ISBN: 9780128037508
eBook ISBN: 9780128037928
Imprint: Academic Press
Published Date: 16th May 2017
Page Count: 774
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The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms.

Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine’s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse.

Key Features

  • Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
  • Illustrated in full color
  • Provides unique full coverage of all aspects of cocaine and its related pathology
  • Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms


Researchers and advanced students in neuroscience, pharmacology, psychopathology, and addiction, as well as drug-abuse workers, public-health workers, and physicians treating addiction

Table of Contents

Part 1. Cocaine, Behavior, and Psychopathological Effects
Part 2. Effects of Cocaine Misuse on Neurological Function and Features
Part 3. Pharmacology and Neuropharmacology
Part 4. Withdrawal and Abstinence
Part 5. Cocaine as a Component of Dual-Use and Polydrug Use or Poly Addictions
Part 6. Cellular Effects and Molecular Biology of Cocaine
Part 7. Treatments for Cocaine Misuse and Dependency and Related Features


No. of pages:
© Academic Press 2017
16th May 2017
Academic Press
Hardcover ISBN:
eBook ISBN:

About the Editor

Victor Preedy

Dr. Preedy is a senior member of King's College London and Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well-being. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is an extremely experienced book editor, having edited influential works including but not limited to The Handbook of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse, The Handbook of Cannabis and Related Pathologies, The Neuroscience of Cocaine, and upcoming titles The Neuroscience of Alcohol, The Neuroscience of Nicotine, and more (all Elsevier).

Affiliations and Expertise

Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK


"...comprehensively covers all aspects of the neurobiology of cocaine and its related pathology. It is an extensive, thorough, in-depth reference regarding all aspects of cocaine's pharmacological, cellular, and molecular effects influencing neurobiological function. Score: 98 - 5 Stars"--Doody's

Ratings and Reviews