Irritable Bowel Syndrome, An Issue of Gastroenterology Clinics of North America

1st Edition, Volume 50-3 - July 24, 2021
Editor: William D. Chey
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 0 9 2 8 - 3
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 0 9 2 9 - 0

In this issue of Gastroenterology Clinics, guest editor William Chey brings his considerable expertise to the topic of Irritable Bowel Syndrome.… Read more

Irritable Bowel Syndrome, An Issue of Gastroenterology Clinics of North America

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In this issue of Gastroenterology Clinics, guest editor William Chey brings his considerable expertise to the topic of Irritable Bowel Syndrome.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Dedication
Epidemiology and Burden of Irritable Bowel Syndrome: An International Perspective
Key points
Introduction
Prevalence rates and diagnostic criteria
Methodological issues
The Rome Foundation Global Epidemiology Study
Prevalence of irritable bowel syndrome in the Rome Foundation Global Epidemiology Study
Comparison of irritable bowel syndrome by rome III versus rome IV diagnostic criteria in Rome Foundation Global Epidemiology Study
Clinics care points
Latest Insights on the Pathogenesis of Irritable Bowel Syndrome
Key points
Introduction
Factors that increase the risk of irritable bowel syndrome
Pathophysiologic mechanisms of irritable bowel syndrome
Summary
Clinics Care Points
Emerging Role of the Gut Microbiome in Irritable Bowel Syndrome
Key points
Introduction
Postinfection irritable bowel syndrome
Small intestinal bacterial overgrowth and irritable bowel syndrome
Microbiome alterations in irritable bowel syndrome
Gut microbiota and the gut-brain axis
Gut microbiota and visceral hypersensitivity
Gut microbiota and gastrointestinal motility
Gut microbiota and intestinal permeability
Gut microbiome and immune activation
Alteration of microbiome mediators affecting gut physiology in irritable bowel syndrome
Microbiome-directed therapies
Summary
Clinics care points
Making a Confident Diagnosis of Irritable Bowel Syndrome
Key points
Introduction
Diagnostic criteria for irritable bowel syndrome
Diagnostic approach to irritable bowel syndrome
Summary
Clinics care points
Diet Interventions for Irritable Bowel Syndrome: Separating the Wheat from the Chafe
Key points
Introduction
The complexity of wheat intolerance in irritable bowel syndrome
Gluten intolerance in irritable bowel syndrome
Is it gluten or fructan intolerance?
The power of the placebo and nocebo effect
Leveraging biomarkers to predict response to diet in irritable bowel syndrome
Low fermentable, oligo-,di-mono-saccharide and polyol diet and irritable bowel syndrome
The low fermentable, oligo-,di-mono-saccharide and polyol diet and nutrient adequacy
Role of histamine intolerance
The sixth fermentable, oligo-,di-mono-saccharide and polyol? Sucrose intolerance
The potential for disordered eating and eating disorders in irritable bowel syndrome
Summary
Clinics care points
Behavioral Strategies for Irritable Bowel Syndrome: Brain-Gut or Gut-Brain?
Key points
Introduction
Burden of irritable bowel syndrome
Factors that contribute to irritable bowel syndrome
Behavioral treatments for irritable bowel syndrome
Gut-directed hypnosis
Age of virtual care
Discussion
Clinics care points
Disclosure
Irritable Bowel Syndrome and Eating Disorders: A Burgeoning Concern in Gastrointestinal Clinics
Key points
Introduction
Eating disorder versus disordered eating
Gastrointestinal disorders as a risk factor for eating disorders
Overview of eating disorder diagnostic criteria
What is known about the overlap of irritable bowel syndrome and eating disorders?
Global gastrointestinal symptoms and eating disorders
Association between irritable bowel syndrome treatment and eating disorders
What is the role of the gastroenterologist?
Limitations
Summary
Clinics care points
Medical Therapies for Diarrhea-Predominant Irritable Bowel Syndrome
Key points
Introduction
Therapies for diarrhea-predominant irritable bowel syndrome approved by the US Food and Drug Administration
Other pharmacotherapies for diarrhea-predominant irritable bowel syndrome not approved by the US Food and Drug Administration
Herbal and supplement therapies for diarrhea-predominant irritable bowel syndrome
Novel and emerging therapies for diarrhea-predominant irritable bowel syndrome
Summary
Clinics care points
Focus on Pharmacotherapy for Irritable Bowel Syndrome with Constipation
Key points
Introduction
Over-the-counter laxatives
Secretagogues
Prokinetics
Summary
Clinics care points
Psychopharmacologic Therapies for Irritable Bowel Syndrome
Key points
Introduction
Central neuromodulators in irritable bowel syndrome
The multidimensional clinical profile
Implementing treatment with central neuromodulators in irritable bowel syndrome
Case 1. Postinfection irritable bowel syndrome with diarrhea, disturbing abdominal pain, and psychosocial comorbidities
Central neuromodulators: therapeutic options
Case 2. Irritable bowel syndrome with constipation worsened by use of opioids
Case 3. Irritable bowel syndrome mixed progressing to centrally mediated abdominal pain syndrome with severe opioid complications
Clinics care points
Disclosure
Complementary and Alternative Medicine Therapies for Irritable Bowel Syndrome
Key points
Introduction
Classification of complementary and alternative medicine therapies
Characteristics of complementary and alternative medicine use for irritable bowel syndrome
Selected complementary and alternative medicine therapies for irritable bowel syndrome
Challenges with complementary and alternative medicine therapies
Recommendations for asking about and counseling patients on complementary and alternative medicine use
Summary
Clinics care points
Disclosure
The Dilemma of Persistent Irritable Bowel Syndrome Symptoms in Patients with Quiescent Inflammatory Bowel Disease
Key points
Introduction
Differences and similarities between irritable bowel syndrome and inflammatory bowel disease
Irritable bowel syndrome in inflammatory bowel disease: magnitude of the problem
Pathophysiology of irritable bowel syndrome and inflammatory bowel disease: some common ground?
The concept of irritable inflammatory bowel disease
Clinical approach of irritable bowel syndrome in inflammatory bowel disease
Treatment options for patients with quiescent inflammatory bowel disease and persistent irritable bowel syndrome symptoms
Summary
Clinics care points
Integrated Care for Irritable Bowel Syndrome: The Future Is Now
Key points
Introduction
The Evolution of Care for Irritable Bowel Syndrome
Integrated care becomes evidence based
Barriers and solutions to integrated care
Summary
Clinics care points

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William D. Chey