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iPSCs in Tissue Engineering - 1st Edition - ISBN: 9780128238097

iPSCs in Tissue Engineering

1st Edition

Editor: Alexander Birbrair
Paperback ISBN: 9780128238097
Imprint: Academic Press
Published Date: 1st August 2021
Page Count: 300
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Table of Contents

1. Delivery strategies for immune checkpoint blockade inhibitors
2. Delivery strategies for ex vivo and in vivo T-cell reprogramming
3. Delivery strategies for ex vivo and in vivo NK cell reprogramming
4. Delivery strategies for tumor-associated macrophage reprogramming
5. Reprogramming lymphocytes for tumor immunotherapy
6. Targeting tumor-associated neutrophils in immunotherapy
7. Targeting tumor-associated fibroblast in immunotherapy
8. Oncolytic viral particle delivery
9. Extracellular vesicles (exosomes) in tumor immunotherapy
10. Nucleic acid-based delivery and reprogramming for tumor immuno-oncology
11. CRISPR-based gene editing in cancer immunotherapy
12. Delivery strategies for glioma immunotherapy
13. Delivery strategies for STING agonists
14. Delivery strategies for cancer vaccine and immunoadjuvant
15. Targeted delivery and reprogramming myeloid-derived suppressor cells (MDSC) in cancer
16. Delivery of radio-immunotherapy for solid tumors
17. Delivery of photo-immunotherapy for cancer
18. Local immunotherapy of cancer and metastasis
19. Delivery strategies to overcome tumor immunotherapy resistance


The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs in Tissue Engineering, Volume 11 addresses how important induced pluripotent stems cells are and how can they be used in patient-specific disease models. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells from various, species such as: bovine, equine, non-human primate, rat, etc., are being used for treatment of different diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

Key Features

  • Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics
  • Covers equine, non-human primate, porcine, canine, prairie vole, rabbit, naked mole rat, and other species
  • Contributed by world-renown experts in the field


Researchers and scientists in stem cell therapy, cell biology, regenerative medicine, and organ transplantation Graduate and undergraduate students in the above fields


No. of pages:
© Academic Press 2021
1st August 2021
Academic Press
Paperback ISBN:

Ratings and Reviews

About the Editor

Alexander Birbrair

Dr. Alexander Birbrair received his bachelor’s biomedical degree from Santa Cruz State University in Brazil. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Then, he joined as a postdoc in stem cell biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine in New York. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA). He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.

Affiliations and Expertise

Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil Department of Radiology, Columbia University Medical Center, Medical Center, USA