Ions-Cyclic Nucleotides-Cholinergy - 1st Edition - ISBN: 9780080231938, 9781483188577

Ions-Cyclic Nucleotides-Cholinergy

1st Edition

Proceedings of the 7th International Congress of Pharmacology, Paris, 1978

Editors: J.C. Stoclet
eBook ISBN: 9781483188577
Imprint: Pergamon
Published Date: 1st January 1979
Page Count: 340
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Description

Advances in Pharmacology and Therapeutics, Volume 3: Ions – Cyclic Nucleotides – Cholinergy covers the proceedings of the Seventh International Congress of Pharmacology, held in Paris in 1978. This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy. Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium. The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP are also looked into. This text presents in its latter part papers on chemical structure and cholinergic activity. This volume will be valuable to students and experts in the field of pharmacology, therapeutics, and related fields.

Table of Contents


Introduction

Ions

Pharmacology of Calcium Homeostasis

The Control of Calcium Metabolism in Health and Disease

Vitamin D and its Metabolites: Physiology, Biochemistry and Pharmacology

Clinical Pharmacology and Application of the Active Forms of Vitamin

Biosynthesis, Metabolism and Mode of Action of Parathyroid Hormone

Calcitonin: From Physiology to Therapeutic Uses

Diphosphonates

Summary

Invited Lectures

Ca Ion and Muscle Contraction

The Sodium Channels in Excitable Membranes

Cyclic Nucleotides

Role of Cyclic Nucleotides in the Regulation of Muscular Tissue Functions

Cyclic Nucleotides and Muscle Function: Introduction

The Possible Role of Cyclic GMP in the Actions of Hormones and Drugs on Smooth Muscle Tone: Effects of Exogenous Cyclic GMP Derivatives

Effect of Nitro-compound Smooth Muscle Relaxants and other Materials on Cyclic GMP Metabolism

Adenylate Cyclase in Heart and Skeletal Muscle

Cyclic Nucleotide Accumulation and Hormonal Modulation of Cardiac Metabolism and Contraction

Possible Regulation of the Calcium Permeability of Cardiac Cell Membranes by Cyclic Nucleotides

Some Characteristics of Low Molecular Weight Phosphoprotein Constituents of Cardiac Sarcoplasmic Reticulum and Sarcolemma

Phosphorylation and Regulation of Contractile Proteins

Evaluation of Cyclic AMP and Cyclic GMP

A Reassessment of the Criteria Used to Involve Cyclic Nucleotides in Hormone and Drug Mechanisms

Radioimmunoassay of Cyclic AMP, Cyclic CMP

The Distribution of Cyclic Nucleotides and their Protein Kinases in Tissues: An Immunocytochemical Approach

Contribution of Theoretical Simulation to the Study of the Cyclic AMP System

Invited Lecture

Cyclic Nucleotides, Phosphorylated Proteins and Drug Actions in the Central Nervous System

Cholinergy

Chemical Structure and Cholinergic Activity

The Use of Affinity Constants for Studying Interactions between Pharmacodynamic Groups and the Muscarinic Receptor

Structure and Activity of some New Muscarine Derivatives and Acetylcholine Analogues

The Conformation and Flexibility of Cholinergic Molecules

An NMR Study of the Conformations of Atropine and Scopolamine Cations in Aqueous Solution

The Conformation of Anti-cholinergic Substances

Biodegradable Neuromuscular Blocking Agents

Effects of Anti-cholinergic Drugs on the Actions of Anti-cholinesterases on Cat Skeletal Muscle

Dual Mechanism of the Anti-dotal Action of Atropine-like Drugs in Poisoning by Organophosphorus Anti-cholinesterases

Index

Details

No. of pages:
340
Language:
English
Copyright:
© Pergamon 1979
Published:
Imprint:
Pergamon
eBook ISBN:
9781483188577

About the Editor

J.C. Stoclet