Ion Channels, Part B - 1st Edition - ISBN: 9780121821944, 9780080884042

Ion Channels, Part B, Volume 293

1st Edition

eBook ISBN: 9780080884042
Imprint: Academic Press
Published Date: 31st July 1998
Page Count: 805


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Table of Contents


J. Xu and M. Li, Methods Used to Study Subunit Assembly of Potassium Channels.

Z.F. Sheng and C. Deutsch, Assembly of Ion Channels.

J.S. Trimmer, Analysis of K+ Channel Biosynthesis and Assembly in Transfected Mammalian Cells. Genetics:

T.M. Ishii, P. Zerr, X-m. Xia, C.T. Bond, J. Maylie, and J.P. Adelman, Site-Directed Mutagenesis.

S. Richard, P. Lory, E. Bourinet, and J. Nargeot, Molecular Physiology of Human Cardiovascular Ion Channels: From Electrophysiology to Molecular Genetics.

R.L. Nakamura and R.F. Gaber, Studying Ion Channels Using Yeast Genetics.

M. Tiethammer and M. Sheng, Identification of Ion Channel-Associated Proteins Using Yeast Two-Hybrid System.

A. Karlin and M.H. Akabas, Substituted-Cysteine Accessibility Method.

R. Horn, Explorations of Voltage-Dependent Conformational Changes Using Cysteine Scanning.

K. Sato and M. Tohyama, Assessment of Distribution of Cloned Ion Channels in Neuronal Tissues. Electrophysiology:

J.W. Hanrahan, Z. Kone, C.J. Mathews, J. Luo, Y. Jia, and P. Linsdell, Patch Clamp Studies of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel.

T.J. Nelson, P.A. Gusev, and D.L. Alkon, Identification of Ion Channel Regulating Proteins by Patch Clamp Analysis.

S.R. Lockery and M.B. Goodman, Tight-Seal Whole-Cell Patch Clamping of Caenorhabditis elegans Neurons.

R.A. Levis and J.L. Rae, Low Noise Patch Clamp Techniques.

D.N. Hilgemann and C.C. Lu, Giant Membrane Patches: Improvements and Applications.

W. Stühmer, Electrophysiological Recordings from Xenopus Oocytes.

E. Stefani and F. Bezanilla, Cut-Open Oocyte Voltage Clamp Technique.

S. Kaneko, A. Akaike, and M. Satoh, Cut-Open Recording Techniques.

F. Bezanilla and E. Stefani, Gating Currents.

J.G. Borst and F. Helmchen, Calcium Influx During Action Potentials.

L.D. Partridge, H.U. Zeilhofer, and D. Swandulla, Combined Whole-Cell and Single-Channel Current Measurement with Quantitative Ca2+ Injection or Fura-2 Measurement of Ca2+.

T. Begenisich, Determining Ion Channel Permeation Properties.

R. Steffan, C. Hennesthal, and S.H. Heinemann, Voltage-Dependent Ion Channels: Analysis of Nonideal Macroscopic Current Data.

S.H. Chung and P.W. Gage, Signal Processing Techniques for Channel Current Analysis Based on Hidden Markov Models.

B.S. Rothberg and K.L. Magleby, Investigating Single-Channel Gating Mechanisms through Analysis of Two-Dimensional Dwell-Time Distributions. Expression Systems:

K. Radford and G. Buell, Expression of Ligand-Gated Ion Channels Using Semliki Forest Virus and Baculovirus.

M.U. Ehrengruber, M. Lanzrein, Y. Xu, M.C. Jasek, D.B. Kantor, E.M. Schuman, H.A. Lester, and N. Davidson, Recombinant Adenovirus-Mediated Expression in Nervous System of Genes Coding for Ion Channels and Other Molecules Involved in Synaptic Function.

M.W. Nowak, J.P. Gallivan, S.K. Silverman, C.G. Labarca, D.A. Dougherty, and H.A. Lester, In Vivo Incorporation of Unnatural Amino Acids into Ion Channels in Xenopus Oocyte Expression System.

T.M. Shih, R.D. Smith, L. Toro, and A.L. Goldin, High-Level Expression and Detection of Ion Channels in Xenopus Oocytes.

P. Stampe and T. Begenisich, Unidirectional Fluxes through Ion Channels Expressed in Xenopus Oocytes.

A.L. Eertmoed, Y.F. Vallejo, and W.N. Green, Transient Expression of Heteromeric Ion Channels. Model Simulations:

M.J. Sutcliffe, A.H. Smeeton, Z.G. Wo, and R.E. Oswald, Molecular Modeling of Ligand-Gated Ion Channels.

S.P. Scott and J.C. Tanaka, Use of Homology Modeling to Predict Residues Involved in Ligand Recognition.

M.S.P. Sansom, Ion Channels: Molecular Modeling and Simulation Studies.

M.E. Green, Computer Simulation and Modeling of Ion Channels.

V. Ardonin and T. Hoshi, Kinetic Models and Simulation: Practical Approaches and Implementation Notes. Subject Index. Author Index.


This volume plus its companion, Volume 294, presents cutting edge techniques for the study of ion channels, ranging from the molecular to the physiological level. These volumes supplement Volume 207 of Methods inEnzymology

Key Features

@introbul:Key Features @bul:* Assembly

  • Genetics
  • Electrophysiology
  • Expression Systems
  • Model Simulations


Biochemists, neurophysiologists, molecular biologists, pharmacologists, biophysicists, cell biologists, geneticists, and microbiologists.


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© Academic Press 1998
Academic Press
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