Ion Channels as Therapeutic Targets, Part A - 1st Edition - ISBN: 9780128047941, 9780128052105

Ion Channels as Therapeutic Targets, Part A, Volume 103

1st Edition

Serial Editors: Rossen Donev
eBook ISBN: 9780128052105
Hardcover ISBN: 9780128047941
Imprint: Academic Press
Published Date: 23rd February 2016
Page Count: 402
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Table of Contents

  1. Proteostasis Maintenance of Cys-Loop Receptors
    Yan-Lin Fu, Ya-Juan Wang and Ting-Wei Mu
  2. Harnessing the Flow of Excitation: TRP, Voltage-Gated Na+, and Voltage-Gated Ca2+ Channels in Contemporary Medicine
    Roman V. Frolov and Matti Weckström
  3. Ion Channels in Neurological Disorders
    Pravir Kumar, Dhiraj Kumar, Saurabh Kumar Jha, Niraj Kumar Jha and Rashmi K. Ambasta
  4. Acid Sensing Ion Channels as Potential Pharmacological Targets in Peripheral and Central Nervous System Diseases
    Beatrice Mihaela Radu, Adela Banciu, Daniel Dumitru Banciu and Mihai Radu
  5. Glutamatergic NMDA Receptor as Therapeutic Target for Depression
    Gislaine Z. Réus, Helena M. Abelaira, Talita Tuon, Stephanie E. Titus, Zuleide M. Ignácio, Ana Lúcia S. Rodrigues and João Quevedo
  6. AMPA Receptors as Therapeutic Targets for Neurological Disorders
    Kevin Lee, Lucy Goodman, Chantelle Fourie, Susan Schenk, Beulah Leitch and Johanna M. Montgomery
  7. pH-Sensitive K+ Currents and Properties of K2P Channels in Murine Hippocampal Astrocytes
    Johannes Weller, Christian Steinhäuser and Gerald Seifert
  8. SUMOylation and Potassium Channels: Links to Epilepsy and Sudden Death
    Hongmei Wu, Xu Chen, Jinke Cheng and Yitao Qi


Ion Channels as Therapeutic Targets is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

Key Features

  • Provides cutting-edge developments in protein chemistry and structural biology
  • Discusses the use of ion channels as therapeutic targets
  • Chapters are written by authorities in their field
  • Targeted to a wide audience of researchers, specialists, and students


Researchers and specialists in protein structure and interactions, cancer biology, psychiatry and mass spectrometry.


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© Academic Press 2016
Academic Press
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Ratings and Reviews

About the Serial Editors

Rossen Donev

Rossen Donev Serial Editor

Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2010 Dr. Donev was appointed Senior Lecturer in Swansea University. Currently he is Head of Research at MicroPharm Ltd, UK and Director of Biomed Consult, UK. He has published more than 60 research papers, has chaired scientific meetings in Molecular Medicine and given plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on design of antibody-based oral treatment of pathological conditions of the colon and small intestines.

Affiliations and Expertise

Swansea University, UK