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Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many of which have a genetic component.
This volume of Advances in Genetics presents a broad and comprehensive overview of the inherited channelopathies in humans, including clinical, genetic and molecular aspects of these conditions. Keeping true to the scope of the serial, novel genomic and modeling research approaches and a review of potential therapeutic approaches for each of these conditions are also incorporated.
Geneticists, molecular biologists, neurobiologists
- No. of pages:
- © Academic Press 2008
- 11th December 2008
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
Praise for Advances in Genetics "Outstanding both in variety and in the quality of its contributions."--NATURE "Can be highly recommended to geneticists, and biologists in general...will prove to be of high importance for the development of the science of genetics."--SCIENCE
GHU Sainte-Justine Research Centre, University of Montreal, Quebec, Canada
Centre of Excellence in Neuromics, CHUM Research Centre, Notre-Dame Hospital Montreal, Quebec, Canada