Description

Introductory Immunology quickly acquaints readers with natural immune responses manifesting in diseases and disorders. The book presents a complete picture of natural defenses to infectious agents, as well as the mechanisms that lead to autoimmune dysfunction. In addition, it examines immunologically based diseases, giving the reader sufficient knowledge to make sound clinical decisions leading to better treatment outcomes.

Introductory Immunology is aimed at researchers, postgraduates, or any scientifically inclined reader interested in immunology. No prior expertise in medical, biochemical, or cellular science is needed to benefit from the clear presentation of immunology concepts in this book.

Key Features

  • Quick, concise introduction to immunological concepts
  • Breaks down all of immunology into manageable, logically digestible building blocks
  • Geared toward readers without medical, biochemical, or cellular expertise

Readership

Researchers, post-graduates, and an educated audience interested in immunology.

Table of Contents

  • Preface
    • Dedication
    • Preface
    • Acknowledgments
  • Chapter 1. A Functional Overview of the Immune System and Immune Components
    • Immune Homeostasis
    • Self vs. Non-Self
    • Innate and Adaptive Immunity
    • Anatomy of the Immune System
    • Cells of the Immune System
    • First Line Defenders: The Myeloid Cells
    • Adaptive Avengers: The Lymphoid Cells
    • Lymphocytes
    • Cluster of Differentiation
    • Summary
  • Chapter 2. The Inflammatory Response
    • Inflammation
    • Initiation of the Inflammatory Response
    • Role of Antibodies in Inflammation
    • Biological Functions of Complement
    • Activation and Directed Migration of Leukocytes
    • Pathogen Recognition and Cytokine Signaling
    • Feedback and Adaptation from a Distance
    • Summary
  • Chapter 3. The B Lymphocyte and the Humoral Response
    • B Lymphocytes Produce Antibodies
    • Structural Characteristics of Immunoglobulins
    • Immunoglobulin Nomenclature
    • Biologic Properties of Antibody Isotypes
    • Kinetics of Antibody Response
    • Membrane-Bound Immunoglobulin
    • Development of B Cells
    • Gene Recombination
    • Development and Selection of Mature B Cells
    • Activation and Differentiation of B Cells
    • Summary
  • Chapter 4. T Lymphocytes: Ringleaders of Adaptive Immune Function
    • T Lymphocytes: Specific and Long-Lasting Immunity
    • The T Cell Receptor
    • T Cell Development
    • Antigen Recognition by T Cells: Requirement of Major Histocompatability Molecules
    • T Lymphocyte Functions
    • Events Involved in T Lymphocyte Activation
    • Role of T Cells in B Cell Activation
    • Cytotoxic T Cell Effectors
    • Innate Lymphocytes and Superantigens
    • Summary
  • Chapter 5. How We Defend Against Infect

Details

No. of pages:
172
Language:
English
Copyright:
© 2015
Published:
Imprint:
Academic Press
eBook ISBN:
9780124200722
Print ISBN:
9780124200302

About the author

Jeffrey Actor

Jeffrey K. Actor, PhD is a professor and Medical Immunology Course Director in the Department of Pathology and Laboratory Medicine at the University of Texas Health Center at Houston. Dr. Actor received his PhD from the University of Massachusetts. His research interests include examination of host immune responses during parasitic disease, understanding proinflammatory and regulatory cytokines during mycobacterial infections, vaccine development, and molecular mechanisms of Lactoferrin immunomodulation.

Affiliations and Expertise

Department of Pathology and Laboratory Medicine, University of Texas-Houston Medical School, USA

Reviews

"This book is, in many ways, a dictionary of immunological terms and concepts. It would probably be a good review for undergraduate students, nursing students, and medical and dental students. Rating: 66 - 2 Stars"--Doody's.com, February 20, 2015