Introduction to Clinical Oncology

1st Edition - January 1, 1981
Editors: Stanley T. Crooke, Archie W. Prestayko
Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 2 - 6 7 9 0 - 6

9780121978020 Cancer and Chemotherapy, Volume II: Introduction to Clinical Oncology provides the basic framework for understanding antineoplastic drugs. The use of… Read more

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9780121978020 Cancer and Chemotherapy, Volume II: Introduction to Clinical Oncology provides the basic framework for understanding antineoplastic drugs. The use of chemotherapeutics in the treatment of the most common human malignancies, including leukemias and lymphomas, is discussed. Solid tumors such as those affecting the breast and lung, head and neck, brain and spinal cord are also considered. Comprised of 17 chapters, this volume begins with an overview of leukemias and lymphomas, including their incidence, pathology, and clinical features. The discussion then turns to solid tumors such as breast and lung carcinoma; head and neck cancers; cancer of the brain and spinal cord; gastrointestinal, genitourinary, and gynecological cancers; and malignant melanoma. The next section is devoted to nutritional and infectious disease aspects of cancer and examines infections that arise in the cancer patient, particularly pneumonia and septicemia. The diagnosis of and therapy for these infections are outlined, along with granulocyte transfusion and prophylaxis of infection. The final chapter deals with nutrition in cancer patients and describes the link between cancer and malnutrition as well as the mechanisms of cancer-associated malnutrition. The advantages and methods of nutritional support for cancer patients are also highlighted. This book should be a valuable resource for oncologists.

List of Contributors

General Preface

Preface to Volume II

Part I Leukemias and Lymphomas

1 The Acute Leukemias

I. Introduction

II. Incidence

III. Classification

IV. Predisposing Factors

V. Presenting Features

VI. Differential Diagnosis

VII. Laboratory Features

VIII. General Therapeutic Considerations

IX. General Clinical Considerations

X. Prognostic Factors

XI. Conclusions

References

2 Hairy Cell Leukemia

I. Definition

II. Incidence with Age and Sex Ratio

III. Pathology

IV. Pathogenesis

V. Clinical Features

VI. Laboratory Features

VII. Treatment

VIII. Course of Disease

IX. Summary

References

3 Chronic Lymphocytic Leukemia

I. Definition

II. Epidemiology

III. Etiologic Features

IV. Pathologic Observations

V. Pathogenesis

VI. Clinical Features

VII. Laboratory Features

VIII. Differential Diagnosis

IX. Treatment

X. Prognostic Factors

XI. Course of Disease

References

4 Chronic Myelocytic Leukemia

I. Special Characteristics

II. Clinical Features

III. Clinical Course

IV. Summary and Conclusions

References

5 The Lymphomas

I. Introduction

II. Hodgkin's Disease

III. Non-Hodgkin's Lymphomas

IV. Conclusion

References

Part II Solid Tumors

6 Carcinoma of the Breast

I. Introduction

II. Incidence and Causative Factors

III. Pathology

IV. Clinical Presentation

V. Prognostic Features

VI. Clinical Course of Metastatic Breast Cancer

VII. Surgical Therapy

VIII. Radiation Therapy

IX. Hormonal Therapy

X. Chemotherapy

XI. Discussion

References

7 Clinical Presentations of Gastrointestinal Cancer

I. Large-Bowel Carcinoma

II. Carcinoma of the Pancreas

III. Carcinoma of the Stomach

References

8 Cancers of the Head and Neck

I. Introduction

II. Incidence

III. Etiology

IV. Histopathology and Spread

V. Clinical Manifestations

VI. Diagnosis

VII. Clinical Staging

VIII. Management

IX. Conclusions

References

9 Carcinoma of the Lung

I. Introduction

II. Classification

III. Evaluation of Lung Cancer

IV. Management of Non-Small-Cell Anaplastic Cancer

V. Management of Metastatic Non-Small-Cell Anaplastic Lung Cancer

VI. Evaluation and Management of Small-Cell Anaplastic Carcinoma

VII. Conclusion

References

10 Clinical Characteristics of Cancer in the Brain

I. Introduction

II. Tumors of the Brain

III. Meningeal Carcinomatosis

IV. Tumors of the Spinal Cord

References

11 Genitourinary Cancer

I. Introduction

II. Renal Carcinoma

III. Carcinoma of the Renal Pelvis

IV. Carcinoma of the Ureter

V. Female Urethral Carcinoma

VI. Male Urethral Carcinoma

VII. Penile Carcinoma

VIII. Testicular Tumors

IX. Bladder Cancer

X. Prostate Cancer

References

12 Gynecological Cancers

I. Introduction

II. Ovarian Cancer

III. Cancer of the Cervix

IV. Endometrial Carcinoma

References

13 Malignant Melanoma

I. Introduction

II. Epidemiology

III. Pathology

IV. Clinical Findings

V. Diagnosis

VI. Prognosis

VII. Treatment

VIII. Conclusion

References

14 The Sarcomas

I. Introduction

II. Diagnosis

III. Soft Tissue Sarcomas

IV. Sarcomas of Bone

V. Conclusion

References

15 Pediatric Cancer

I. Introduction

II. Tumors

III. Conclusions

Part III Nutritional and Infectious Disease Aspects of Cancer

16 Infectious Complications in the Cancer Patient

I. Introduction

II. Types of Infection in Cancer Patients

III. Diagnosis of and Therapy for Infection

IV. Therapy for Nonbacterial Infections

V. Granulocyte Transfusion

VI. Prophylaxis of Infection

VII. Conclusions

References

17 Nutrition in Cancer Patients

I. Introduction

II. Cancer-Malnutrition Associations

III. Mechanisms of Cancer-Associated Malnutrition

IV. Advantages of Nutritonal Support

V. Methods of Nutritional Support

VI. Conclusion

References

Index