Introduction to Clinical Chemistry

Introduction to Clinical Chemistry presents the physiological background for a number of investigations. It discusses the principles and analytical techniques in clinical chemistry. It addresses the basic understanding of chemical pathology. Some of the topics covered in the book are basic principles of metabolic chemistry; disorders of carbohydrate metabolism; nitrogen metabolism; inborn errors of metabolism; chemical endocrinology; assessment of hormonal function; liver function; the formation of bile; and the synthesis and metabolism of amino acids and protein. The storage of carbohydrates and removal of toxic substances from the body are covered. The assessment of liver function is discussed. The text describes the renal function and acid-base metabolism. A study of the renal tubular reabsorption and excretion is presented. A chapter is devoted to the hydrogen ion concentration and analytical techniques in potentiometric determination. Another section focuses on the measurement of osmolality. The book can provide useful information to scientists, physicists, doctors, students, and researchers.

Preface 1 Basic Principles of Metabolic Biochemistry Carbohydrate Metabolism Lipid Metabolism Nitrogen Metabolism 2 Chemical Endocrinology Introduction The Pituitary The Thyroid The Parathyroid Glands The Pancreas The Adrenal (Suprarenal) Glands The Testes The Ovaries Gastrointestinal Hormones Assessment of Hormonal Function 3 Liver Function Anatomy Function Assessment of Liver Function 4 Renal Function and Acid-Base Metabolism Anatomy Function Assessment of Renal Function 5 Analytical Techniques and Clinical Chemistry Potentiometric Determination Spectroscopy Spectrophotometry The Measurement of Osmolality Immunological Techniques Chromatographie Separation Protein Electrophoresis Radioisotope Technique 6 Basic Principles of Laboratory Investigations Bilirubin Calcium Cholesterol Creatine and Creatinine Drugs and Poisons Enzyme Determination Glucose Hormones Phosphate Proteins Renal Calculi Triglycerides Urea 7 Management in Clinical Chemistry The Maintenance of Equipment And Supplies Ergonomics Safety Confidence in Chemical Analysis Work Simplification and Mechanization The Introduction of New Methods References Index