Introduction to Biomedical Engineering

3rd Edition

Authors: John Enderle Joseph Bronzino
Hardcover ISBN: 9780123749796
eBook ISBN: 9780080961217
Imprint: Academic Press
Published Date: 7th March 2011
Page Count: 1272
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Table of Contents



Contributors to the Third Edition

Contributors to the Second Edition

Contributors to the First Edition

Chapter 1. Biomedical Engineering

1.1. The Evolution of the Modern Health Care System

1.2. The Modern Health Care System

1.3. What Is Biomedical Engineering?

1.4. Roles Played by the Biomedical Engineers

1.5. Recent Advances in Biomedical Engineering

1.6. Professional Status of Biomedical Engineering

1.7. Professional Societies

Chapter 2. Moral and Ethical Issues

2.1. Morality and Ethics: A Definition of Terms

2.2. Two Moral Norms: Beneficence and Nonmaleficence

2.3. Redefining Death

2.4. The Terminally Ill Patient and Euthanasia

2.5. Taking Control

2.6. Human Experimentation

2.7. Definition and Purpose of Experimentation

2.8. Informed Consent

2.9. Regulation of Medical Device Innovation

2.10. Marketing Medical Devices

2.11. Ethical Issues in Feasibility Studies

2.12. Ethical Issues in Emergency Use

2.13. Ethical Issues in Treatment Use

2.14. The Role of the Biomedical Engineer in the FDA Process

Chapter 3. Anatomy and Physiology

3.1. Introduction

3.2. Cellular Organization

3.3. Tissues

3.4. Major Organ Systems

3.5. Homeostasis

Chapter 4. Biomechanics

4.1. Introduction

4.2. Basic Mechanics

4.3. Mechanics of Materials

4.4. Viscoelastic Properties

4.5. Cartilage, Ligament, Tendon, and Muscle

4.6. Clinical Gait Analysis

4.7. Cardiovascular Dynamics

Chapter 5. Biomaterials

5.1. Materials in Medicine: From Prosthetics to Regeneration

5.2. Biomaterials: Types, Properties, and Their Applications

5.3. Lessons from Nature on Biomaterial Design and Selection

5.4. Tissue–B


Introduction to Biomedical Engineering is a comprehensive survey text for biomedical engineering courses. It is the most widely adopted text across the BME course spectrum, valued by instructors and students alike for its authority, clarity and encyclopedic coverage in a single volume.

Biomedical engineers need to understand the wide range of topics that are covered in this text, including basic mathematical modeling; anatomy and physiology; electrical engineering, signal processing and instrumentation; biomechanics; biomaterials science and tissue engineering; and medical and engineering ethics.

Enderle and Bronzino tackle these core topics at a level appropriate for senior undergraduate students and graduate students who are majoring in BME, or studying it as a combined course with a related engineering, biology or life science, or medical/pre-medical course.

NEW: Each chapter in the 3rd Edition is revised and updated, with new chapters and materials on compartmental analysis, biochemical engineering, transport phenomena, physiological modeling and tissue engineering. Chapters on peripheral topics have been removed and made avaialblw online, including optics and computational cell biology.
NEW: many new worked examples within chapters
NEW: more end of chapter exercises, homework problems

NEW: Image files from the text available in PowerPoint format for adopting instructors
Readers benefit from the experience and expertise of two of the most internationally renowned BME educators
Instructors benefit from a comprehensive teaching package including a fully worked solutions manual

Key Features

A complete introduction and survey of BME
NEW: new chapters on compartmental analysis, biochemical engineering, and biomedical transport phenomena

NEW: revised and updated chapters throughout the book feature current research and developments in, for example biomaterials, tissue engineering, biosensors, physiological modeling, and biosignal processing.
NEW: more worked examples and end of chapter exercises

NEW: Image files from the text available in PowerPoint format for adopting instructors

As with prior editions, this third edition provides a historical look at the major developments across biomedical domains and covers the fundamental principles underlying biomedical engineering analysis, modeling, and design

*bonus chapters on the web include: Rehabilitation Engineering and Assistive Technology, Genomics and Bioinformatics, and Computational Cell Biology and Complexity.


Senior undergraduate and graduate level students of biomedical engineering and related courses in biological & life sciences and chemical, mechanical and electrical engineering.


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© Academic Press 2012
Academic Press
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About the Authors

John Enderle Author

John Enderle is among the best known biomedical engineers in the world. He is Editor-in-Chief of the IEEE EMB Magazine (Engineering in Medicine and Biology Society, the key electrical systems-oriented BME society). An electrical engineer by training, he is a Fellow of the Institute of Electrical and Electronics Engineers (IEEE), a past-president of the IEEE Engineering in Medicine and Biology Society, and a Fellow of the American Institute for Medical and Biological Engineering (AIMBE). He is also an ABET program evaluator for bioengineering programs and a member of the American Society for Engineering Education.

Affiliations and Expertise

School of Engineering, University of Connecticut, Storrs, CT, USA

Joseph Bronzino Author

Joseph Bronzino is one of the most renowned biomedical engineers in the world. He is a former president of the IEEE Engineering in Medicine and Biology, and well-known educator. He is editor-in-chief of the Biomedical Engineering Handbook from CRC Press, and is currently editor of the Academic Press Series in Biomedical Engineering. He is the Vernon Roosa Professor of Applied Science at Trinity College in Hartford, Connecticut.

Affiliations and Expertise

Trinity College, Hartford, CT, USA