International Review of Experimental Pathology

International Review of Experimental Pathology

Kidney Disease

1st Edition - December 28, 1988

Write a review

  • Editor: G. W. Richter
  • eBook ISBN: 9781483281704

Purchase options

Purchase options
DRM-free (Mobi, PDF, EPub)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order


International Review of Experimental Pathology, Volume 30, is organized around the theme of renal disease. The choice of renal disease reflects both the author’s personal interest and the realization that there is a need for such a collection of reviews in this area. There are many new books on renal pathology, but almost all have a clinical rather than experimental orientation. The book opens with a chapter on the pathogenesis of experimentally induced renal papillary necrosis and upper urothelial carcinoma. Subsequent chapters deal with the use of cell cultures in the study of renal diseases; mechanisms of cyclosporine nephrotoxicity in humans and animal systems; spontaneously occurring renal diseases in laboratory animals; and the use of video microscopy to define the reactivity of the renal microvasculature and the hydraulic permeability of the glomerular capillaries. This book will be of interest to a diverse group of readers interested in renal disease. This broad spectrum of potential readership is reflected in the list of contributors which includes, in addition to pathologists, nephrologists, anatomists, veterinarians, and experimental chemists. This volume will also be of interest to transplant surgeons and to pediatricians specializing in renal disease.

Table of Contents

  • Preface

    Experimentally Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma

    I. Introduction

    II. Renal Papillary Necrosis and Upper Urothelial Carcinoma in Humans

    III. Experimentally Induced Renal Papillary Necrosis

    IV. Use of Model Papillotoxic Probes to Study the Pathogenesis and Secondary Development of Renal Papillary Necrosis

    V. Biochemical Interpretation of the Pathogenesis and Secondary Consequences of Renal Papillary Necrosis

    VI. Renal Papillary Necrosis and Upper Urothelial Carcinoma

    VII. Summary of the Pathogenesis of Experimentally Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma

    VIII. Remaining Questions


    The Contribution of Cell Culture to the Study of Renal Diseases

    I. Introduction

    II. Glomerular Cell Culture

    III. Tubular Cell Culture


    Cyclosporine Nephrotoxicity

    I. Introduction

    II. Experimental Models of Cyclosporine Nephrotoxicity

    III. Clinical Cyclosporine Nephrotoxicity

    IV. Future Directions and Unanswered Questions


    Glomerular Antigens in Experimental Glomerulonephritis

    I. Models of Glomerulonephritis

    II. Structure and Function of the Glomerulus

    III. Immune Mechanisms in the Pathogenesis of Glomerulonephritis

    IV Antigens in Experimental Glomerulonephritis

    V Genetic Influences

    VI. Conclusion


    Spontaneous Renal Disease in Laboratory Animals

    I. Introduction

    II. Rat

    III. Mouse

    IV. Hamster

    V Rabbit

    VI. Guinea Pig

    VII. Dog

    VIII. Monkey


    The Use of Video Imaging Techniques to Study Ultrafiltration and Blood Flow in the Normal and Diseased Kidney

    I. Background

    II. Documentation of Filtration by Isolated Glomeruli

    III. Studies of Isolated Renal Microvessels

    IV Observations of Glomeruli during In Situ Perfusion

    V Studies of Blood-Perfused Juxtamedullary Nephrons

    VI. Documentation of Medullary Blood Flow

    VII. Prospects for the Future


    Chemically Induced Renal Epithelial Neoplasia in Experimental Animals

    I. Introduction

    II. Renal Tubule Epithelial Cell Neoplasia



Product details

  • No. of pages: 410
  • Language: English
  • Copyright: © Academic Press 1988
  • Published: December 28, 1988
  • Imprint: Academic Press
  • eBook ISBN: 9781483281704

About the Editor

G. W. Richter

Ratings and Reviews

Write a review

There are currently no reviews for "International Review of Experimental Pathology"