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International Review of Connective Tissue Research
Volume 4
1st Edition - January 1, 1968
Editor: David A. Hall
Language: English
eBook ISBN:9781483195025
9 7 8 - 1 - 4 8 3 1 - 9 5 0 2 - 5
International Review of Connective Tissue Research covers a broad range of aspects of connective tissue metabolism and structure, and other relevant material in the field of…Read more
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International Review of Connective Tissue Research covers a broad range of aspects of connective tissue metabolism and structure, and other relevant material in the field of connective tissue research. The book discusses topics on the immunological reactions of collagen macromolecules and their degradation products; the factors involved in the specific control of collagen protein synthesis; effect of ionizing radiation on connective tissue components; and the physical properties of connective tissue. Physiologists, pathologists and researchers in the field of medicine will find the book invaluable.
Contributors Preface
Contents of Previous Volumes
Tentative Contents of Subsequent Volumes
Immunology of Collagen
I. Introduction
II. Collagen Purity and Immunological Specificity
III. Amino Acid Composition and Structure of Collagen
IV. Antigenicity of Collagen and Collagen Derivatives
V. Antigenicity of Synthetic Polypeptides Related to Collagen
VI. Antigenicity of Gelatin and Gelatin Derivatives
VII. Immunological Relationships of Collagen and Other Components of Connective Tissue
VIII. Auto- and Isoantibodies to Collagen in Diseases of Connective Tissue
IX. Pathogenicity of Anticollagen Antibodies
X. Summary and Conclusions
References
Collagen Biosynthesis at the Ribosomal Level
I. Collagen-Nucleic Acid Complexes
II. Ribonucleic Acid and Collagen Synthesis
III. Collagen Formation on Polyribosomes
IV. Messenger Ribonucleic Acid
V. The Substrate for Hydroxylation
References
Control of Collagen Biosynthesis
Introduction
I. Conditions for the Specific Control of Biosynthesis of Collagenous Proteins
II. Relation of Intermediary Metabolism to Collagen Synthesis
III. Effect of Proline, Its Analogs, and Other Amino Acids on Collagen Protein Synthesis
IV. Antibiotics and Collagen Synthesis
V. Metals and Collagen Synthesis
VI. Effect of Chelating Agents
VII. Hydroxyproline- and Hydroxylysine-Deficient Collagen
VIII. Collagen Hydroxylase
IX. Ascorbic Acid as the Factor Controlling Protein Synthesis
X. Influence of the Partial Tension of Oxygen
XI. Further Reagents Controlling Collagen Formation
XII. Conclusion
XIII. Appendix: Formulas of Substances Discussed
References
Copper and Connective Tissue Metabolism
I. Introduction
II. The Metabolic Role of Copper
III. The Connective Tissues in Copper Deficiency
IV. Biogenesis of Connective Tissues
V. Relation of Copper to Connective Tissue Metabolism
References
Effect of Ionizing Radiation on Connective Tissue Components
I. Introduction
II. Interaction of Ionizing Radiation with Matter
III. Irradiation of Fibrous Connective Tissue
IV. Irradiation of Ground Substance
V. Irradiation of Cellular Components
VI. Aging and Radiation
VII. Chemical Protection of Tissues against Radiation
VIII. Concluding Remarks
References
Physical Properties of Collagen Fibers
I. Introduction
II. Crystalline Collagen
III. Hydration
IV. Mechanical Properties
V. Noncrystalline Collagen
VI. Summary
References
Author Index
Subject Index
No. of pages: 392
Language: English
Edition: 1
Published: January 1, 1968
Imprint: Academic Press
eBook ISBN: 9781483195025
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