International Review of Connective Tissue Research - 1st Edition - ISBN: 9780123637079, 9781483191690

International Review of Connective Tissue Research

1st Edition

Volume 7

Editors: David A. Hall D. S. Jackson
eBook ISBN: 9781483191690
Imprint: Academic Press
Published Date: 28th April 1976
Page Count: 344
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International Review of Connective Tissue Research, Volume 7 focuses on the structural aspects of the connective tissues and their compounds. This book reviews the data concerning the primary structure of collagen and explores the physical features of elastin. Organized into six chapters, this volume begins with an overview of the amino acid sequence of collagen. This text then examines the relationship of the structure and function of elastic tissues and reviews the usefulness of immunological methods when applied to structural studies. Other chapters consider the substantial progress in the elucidation of the antigen determinants of the collagen molecule. This book discusses as well the immunological properties of collagen that may have considerable bearing on the causes of some connective tissue diseases. The final chapter deals with the extensive investigations into glycoproteins in various connective tissues of various species at various ages. This book is a valuable resource for biochemists and physicians.

Table of Contents



Contents of Previous Volumes

The Primary Structure Of Collagen

I. Introduction

II. Methodical Aspects

III. Evolution of the Structural Analysis of Collagen and Its Present State

IV. The Sequence of Residues in Collagen Type I

V. The Sequence of Collagens Type II and Type III

VI. Implications of the Amino Acid Sequence for Formation Fibrils and Crosslinks

VII. Concluding Remarks


Immunochemistry of Collagens and Procollagens

I. Introduction

II. Antigenic Determinants in the Terminal Regions of Collagen

III. Collagen Conformation and Antigenic Specificity

IV. Procollagen: Modification of the Immune Response by a Globular Moiety

V. Immunogenicity of Collagen: Cellular and Structural Basis

VI. Concluding Remarks


Enzymic Degradation of Collagen

I. Preamble

II. Nomenclature

III. Enzymes Degrading Gelatin

IV. Enzymes Degrading Soluble Type I Collagen In Vitro

V. Insoluble Type I Collagen

VI. Type II Collagen

VII. Type III Collagen

VIII. Type IV Collagen (Basement Membrane)

IX. Miscellaneous Collagens

X. Summary


Elastin Structure in Health and Disease

I. Introduction

II. Historical Aspects of Elastin

III. Structural Studies of Elastin and Tropoelastin

IV. A Molecular Model for Elastin

V. Elastin Involvement in Aging and Atherosclerosis

VI. Special Methods in Isolation of Elastin and Tropoelastin


The Physical Properties of Elastic Tissue

I. Introduction

II. The Morphology of Elastic Tissues

III. Elastin: Composition

IV. Elastin: Structure

V. Elastin: The Elastic Mechanism

VI. The Mechanical Properties of Elastic Tissue


Glycoproteins of the Connective Tissue Matrix

I. Introduction

II. Methods of Isolation

III. Individual Tissues

IV. Biosynthesis

V. Concluding Remarks


Subject Index


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© Academic Press 1976
Academic Press
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About the Editor

David A. Hall

D. S. Jackson

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