International Review of Cell and Molecular Biology - 1st Edition - ISBN: 9780128002551, 9780128004470

International Review of Cell and Molecular Biology, Volume 309

1st Edition

Editors: Kwang Jeon
eBook ISBN: 9780128004470
Hardcover ISBN: 9780128002551
Imprint: Academic Press
Published Date: 21st January 2014
Page Count: 408
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Table of Contents

Chapter One: Mouse Primordial Germ Cells

1 Introduction

2 Current Model of the Origin of Primordial Germ Cells (PGCs) and Segregation from Soma

3 Flaws in Current Model of PGC Origin and Segregation

4 Comparison of Mammalian Germline Program to That Across Metazoa

5 Embryonic–Extraembryonic Interface and Fetal–Umbilical Connection: PGCs and ACD

6 Loss/Mislocalization of PGCs and Associated Posterior Defects

7 Perspectives

8 Conclusions


Chapter Two: Microtubule Plus-End Tracking Proteins and Their Roles in Cell Division

1 Introduction

2 Microtubules in Cell Division

3 Families of Microtubule Plus-End-Tracking Proteins (+TIPs)

4 Recognition of Microtubule Plus Ends by +TIPs

5 +TIPs in Mitosis

6 Concluding Remarks


Chapter Three: Unicellular Eukaryotes as Models in Cell and Molecular Biology

1 Introduction

2 What is Special About Unicellular Models

3 Unicellular Models for Organelle Biogenesis

4 Models for Epigenetic Phenomena

5 Exploring Potential of New Model Systems

6 Epilogue


Chapter Four: Genetic Mechanisms of Allopolyploid Speciation Through Hybrid Genome Doubling

1 Introduction

2 Plant Polyploidy and Allopolyploidy

3 Pre- and Postzygotic Barriers in Plant Hybridization

4 Unreduced Gametes

5 Allopolyploid Genome Alteration

6 Concluding Remarks

Chapter Five: New Insights into the Role of Plg-RKT in Macrophage Recruitment

1 Introduction

2 The PLG Activation System

3 General Characteristics of Plasminogen Receptors

4 Role of PLG in Macrophage Recruitment In Vivo

5 Proteomics-Based Discovery of Plg-RKT

6 Structure and Distribution of Plg-RKT

7 Plg-RKT and Plasminogen Receptor Functions

8 Interplay Among Plasminogen Receptors in Macrophage Migration in Induced Peritonitis

9 Conclusions


Chapter Six: ATP-Binding Cassette and Multidrug and Toxic Compound Extrusion Transporters in Plants

1 Introduction

2 ABC Transporters

3 MATE Transporters

4 Functions of ABC and MATE Transporters in Plants

5 Concluding Remarks

Chapter Seven: Role of p-21-Activated Kinases in Cancer Progression

1 Introduction

2 Group I PAK Overview

3 Group II PAK Overview

4 Targeting PAKs in Cancer

5 Concluding Remarks



International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Key Features

  • Authored by some of the foremost scientists in the field
  • Provides comprehensive reviews and current advances
  • Wide range of perspectives on specific subjects
  • Valuable reference material for advanced undergraduates, graduate students and professional scientists



Cell biologists, molecular biologists, developmental biologists, physiologists (organ level), biomedical scientists, biochemists studying cell-cell interactions, cell variation and evolution, students and researchers.


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© Academic Press 2014
Academic Press
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About the Editors

Kwang Jeon Editor

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and Expertise

University of Tennessee, Knoxville, TN, USA