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International Review of Cell and Molecular Biology - 1st Edition - ISBN: 9780128048061, 9780128052228

International Review of Cell and Molecular Biology, Volume 325

1st Edition

Serial Editor: Kwang Jeon
eBook ISBN: 9780128052228
Hardcover ISBN: 9780128048061
Imprint: Academic Press
Published Date: 26th May 2016
Page Count: 320
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Table of Contents

Chapter One: New Insights Into Roles of Ubiquitin Modification in Regulating Plastids and Other Endosymbiotic Organelles

  • Abstract
  • 1. Introduction
  • 2. Ubiquitin–Proteasome System
  • 3. Regulation of Endosymbiotic Organelles by Ubiquitin
  • 4. Concluding Remarks
  • Acknowledgments

Chapter Two: New Insights Into the Role of Ubiquitylation of Proteins

  • Abstract
  • 1. Introduction
  • 2. Protein Ubiquitylation
  • 3. New Insights Into Noncanonical Ubiquitylation
  • 4. New Insights Into Chain Formation and Unconventional Ubiquitin Chains
  • 5. Crosstalk Between Ubiquitin and Other Posttranslational Modifications
  • 6. New Tools and Developments for Ubiquitylation Studies
  • 7. Concluding Remarks
  • Acknowledgments

Chapter Three: Heterogeneity, Cell Biology and Tissue Mechanics of Pseudostratified Epithelia: Coordination of Cell Divisions and Growth in Tightly Packed Tissues

  • Abstract
  • 1. Introduction
  • 2. Apical Nuclear Migration in Pseudostratified Epithelia
  • 3. Tissue-Wide Properties of PSE
  • 4. Conclusions
  • Acknowledgments

Chapter Four: New Insight Into the Roles of Membrane Microdomains in Physiological Activities of Fungal Cells

  • Abstract
  • 1. Introduction: History of Lateral Microdomains in Fungal Membranes
  • 2. Contemporary List of Fungal Membrane Microdomains
  • 3. Formation and Maintenance of Membrane Microdomains
  • 4. Physiological Relevance of Laterally Segregated Membrane Contents
  • 5. Concluding Remarks and Perspectives
  • Acknowledgments

Chapter Five: Development and Application of Functionalized Protein Binders in Multicellular Organisms

  • Abstract
  • 1. Introduction
  • 2. Protein Binder Scaffolds
  • 3. Use of Protein Binders in Basic Science
  • 4. Use of Protein Binders in Multicellular Organisms
  • 5. Conclusions and Outlook
  • Acknowledgment

Chapter Six: Heparan Sulfate: Biosynthesis, Structure, and Function

  • Abstract
  • 1. Introduction
  • 2. Heparan Sulfate Proteoglycans
  • 3. Biosynthesis of Heparan Sulfate
  • 4. Genetic Defects in Heparan Sulfate
  • 5. Structural Properties of Heparan Sulfate in Interaction With Proteins
  • 6. Heparan Sulfate Proteoglycans and Diseases
  • 7. Therapeutical Potential
  • 8. Concluding Remarks
  • Acknowledgments

Chapter Seven: Functions of Heparan Sulfate Proteoglycans in Development: Insights From Drosophila Models

  • Abstract
  • 1. Introduction
  • 2. Glypicans
  • 3. Syndecan and Perlecan
  • 4. Heparan Sulfate Biosynthesis
  • 5. Concluding Remarks


International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology, and includes articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.

The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.

Key Features

  • Provides comprehensive reviews and current advances
  • Presents a wide range of perspectives on specific subjects
  • Valuable reference material for advanced undergraduates, graduate students, and professional scientists


Cell biologists, molecular biologists, developmental biologists, and physiologists (organ level), biomedical scientists and biochemists studying cell-cell interactions, cell variation and evolution students and researchers.


No. of pages:
© Academic Press 2016
26th May 2016
Academic Press
eBook ISBN:
Hardcover ISBN:

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About the Serial Editor

Kwang Jeon

Kwang Jeon

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and Expertise

University of Tennessee, Knoxville, TN, USA