International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology

1st Edition - January 7, 2014

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  • Editor: Kwang Jeon
  • eBook ISBN: 9780128005866

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International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a world-wide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists. Impact factor for 2012: 4.973.

Key Features

  • Authored by some of the foremost scientists in the field
  • Provides comprehensive reviews and current advances
  • Wide range of perspectives on specific subjects
  • Valuable reference material for advanced undergraduates, graduate students and professional scientists


Cell biologists, molecular biologists, developmental biologists, physiologists (organ level), biomedical scientists, biochemists studying cell-cell interactions, cell variation and evolution, students and researchers.

Table of Contents

  • Contributors
    Chapter One: Structure and Function of POTRA Domains of Omp85/TPS Superfamily

    1 Introduction

    2 Omp85/TPS Superfamily Architecture

    3 Function of Omp85 Family of Proteins

    4 Functions of Two-Partner Secretion B Proteins

    5 Phototrophic Members of Omp85/TPS

    6 POTRA Domains Mode of Action

    7 Concluding Remarks

    Chapter Two: Molecular Cell Biology and Immunobiology of Mammalian Rod/Ring Structures

    1 Introduction

    2 Conserved RR Structures Across Species

    3 Known Components of RR

    4 Biological Function of RR

    5 Immunobiology of RR—Autoimmune Response

    6 Concluding Remarks and Future Perspectives


    Chapter Three: Modulation of Glycan Recognition by Clustered Saccharide Patches

    1 Introduction: Glycome Complexity in Nature

    2 Glycan Recognition by GBPs

    3 Concept of CSPs

    4 Evidence for CSPs on Heavily Glycosylated Proteins

    5 Clustered Patches of Sialylated Gangliosides on Cell Surfaces

    6 Clustered Patches of Sialylated Glycoproteins on Cell Surfaces

    7 Enzyme Recognition of Clustered Glycans: O-Sialoglycoprotein Endopeptidase

    8 CSPs on Pathogens

    9 Glycosynapses: Cell Interactions and Signaling via CSPs

    10 Recognition of Combined Saccharide–Peptide Patches

    11 Experimental Recreation of CSPs

    12 Conclusions and Perspectives


    Chapter Four: New Insights into the Molecular Mechanisms of Mitosis and Cytokinesis in Trypanosomes

    1 Introduction

    2 Cell Structure of T. brucei

    3 Cell Cycle of T. brucei

    4 Regulation of Mitosis

    5 Mechanisms of Cytokinesis

    6 Conclusions and Perspectives


    Chapter Five: Reprogramming and Carcinogenesis—Parallels and Distinctions

    1 Introduction

    2 Overview of Reprogramming Methods

    3 Reprogramming, Antiproliferative Response, Apoptosis, and Senescence

    4 Reprogramming and Autophagy

    5 Reprogramming Factors and Carcinogenesis

    6 Stemness Factors as Transcription Factors—Effects in Transformation and Reprogramming

    7 Differences and Similarities between iPS Cells and CSC

    8 Interaction of Biomaterials with Cells

    9 Closing Remarks


    Chapter Six: New Insights into Functions, Regulation, and Pathological Roles of Tight Junctions in Kidney Tubular Epithelium

    1 Introduction

    2 Structure and Function of TJs

    3 “Nonclassic” Functions of TJs

    4 Regulation of TJs

    5 Kidney Disease and TJs

    6 Concluding Remarks


    Chapter Seven: Making of a Retinal Cell: Insights into Retinal Cell-Fate Determination

    1 Introduction

    2 Retinal Cell-Fate Specification

    3 Extrinsic Signaling

    4 Intrinsic Signals and Retinal Development

    5 Recent Discoveries Contributing to Retinal Fate Decisions

    6 “Omics” Approaches to Understanding Retinal Cell-Fate Decisions

    7 Additional Factors Contributing to Retinal Fate Determination

    8 Recent Perspectives

    Chapter Eight: Adhesion Networks of Cnidarians: A Postgenomic View

    1 Introduction

    2 Cnidarian Genomes

    3 The Anatomy of N. vectensis and Hydra Polyps

    4 ECM in Cnidarians

    5 Functional Importance of Cell–ECM Interactions for Tissue Organization and Regeneration in Cnidarians

    6 Cell–Cell Adhesion Molecules in Cnidarians

    7 Conclusions and Future Directions



Product details

  • No. of pages: 400
  • Language: English
  • Copyright: © Academic Press 2014
  • Published: January 7, 2014
  • Imprint: Academic Press
  • eBook ISBN: 9780128005866

About the Editor

Kwang Jeon

Kwang Jeon
Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and Expertise

University of Tennessee, Knoxville, TN, USA

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