Description

International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.

Key Features

  • Authored by some of the foremost scientists in the field
  • Provides up-to-date information and directions for future research
  • Valuable reference material for advanced undergraduates, graduate students and professional scientists

Readership

Cell biologists, molecular biologists, developmental biologists, physiologists (organ level), biomedical scientists, biochemists studying cell-cell interactions, cell variation and evolution

Table of Contents

Series Page

Contributors

Chapter One. New Insights into Adhesion Signaling in Bone Formation

1 Introduction

2 Cell-Adhesion Receptors in Bone Cells

3 Lessons from Integrin and Integrin-Associated Proteins-Deficient Mice

4 Integrin-Dependent Signaling in Osteoblasts

5 Mechanotransduction in Bone Cells

6 Conclusion and Perspectives

Acknowledgments

References

Chapter Two. New Insights into Roles of Acidocalcisomes and Contractile Vacuole Complex in Osmoregulation in Protists

1 Introduction

2 Acidocalcisomes in Protists

3 Contractile Vacuole Complex

4 Volume Control in T. cruzi

5 Conclusions and Open Questions

Acknowledgments

References

Chapter Three. Functional Roles of Histone Modification, Chromatin Remodeling and MicroRNAs in Arabidopsis Flower Development

1 Introduction

2 Histone Modification in Flower Development

3 Chromatin Remodeling in Flower Development

4 Function of MicroRNAs in Flower Development

5 Concluding Remarks

References

Chapter Four. Thy-1-Interacting Molecules and Cellular Signaling in Cis and Trans

Abbreviations

1 Introduction

2 Thy-1 Molecule

3 Thy-1 Cis-Interacting Molecules and Signaling

4 Trans-Interacting Thy-1 Molecules and Signaling

5 Function of Thy-1 Molecule

6 Concluding Remarks

Acknowledgments

References

Chapter Five. Discovery of Survivin Inhibitors and Beyond: FL118 as a Proof of Concept

1 Introduction

2 Inhibitors That Disrupt Survivin Interactions with Other Proteins

3 Compounds That Inhibit Survivin Expression

4 Compounds with Controversial Effects on Survivin Expression

5 Survivin Inhibitors Discovered by HTS

6 Conclusion Remark

Acknowled

Details

No. of pages:
464
Language:
English
Copyright:
© 2013
Published:
Imprint:
Academic Press
Electronic ISBN:
9780124078444
Print ISBN:
9780124076952

About the editor

Kwang Jeon

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.