International Review of Cell and Molecular Biology, Volume 300

1st Edition

Editors: Kwang Jeon
Hardcover ISBN: 9780124052109
eBook ISBN: 9780124058514
Imprint: Academic Press
Published Date: 31st December 2012
Page Count: 336
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Table of Contents

Series Editors


Chapter One. New Insights into Mechanisms of Stem Cell Daughter Fate Determination in Regenerative Tissues

1 Introduction

2 Stem Cells in Invertebrate Model Systems

3 Characteristics of Mammalian Stem Cells

4 Cancer Cell Dynamics with the Stochastic Cell-State Transition Model

5 Self-Renewal and Differentiation of Stem Cells in Culture

6 Concluding Remarks


Chapter Two. Insights into Skeletal Muscle Development and Applications in Regenerative Medicine

1 Introduction

2 Developmental Myogenesis

3 Muscle Stem Cell Lineages

4 Transcriptional and Posttranscriptional Regulation of Myogenesis

5 Differentiation of Pluripotent Stem Cells Toward Skeletal Muscle

6 Regenerative Myogenesis in Adult Muscle

7 Modeling Muscular Dystrophy and Potential Therapeutic Approaches

8 Conclusions


Chapter Three. Cellular and Molecular Biology of Neuronal Dystonin

1 Introduction to the Cytoskeleton and Cytoskeletal Linking Proteins

2 Dystonin Gene Organization and Isoform Diversity

3 Structural and Molecular Properties of Dystonin

4 Expression and Subcellular Localization

5 Dystonin Deficiency in Murine and Cell Culture Models

6 Dystonin and Human Disease

7 Conclusion and Future Directions


Chapter Four. Kinase–Kinase Interaction and Modulation of Tau Phosphorylation

1 Introduction

2 Multisite Phosphorylation of Tau

3 Proteins of TPPC

4 Modulation of Tau Phosphorylation by a Topographical Mechanism

5 Synergism and Antagonism between Tau Kinases

6 Modulation of Tau Phosphorylation by A Temporal Mechanism

7 Implications of Modulatory Tau Phosphorylation

8 Concluding Remarks



International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2011: 4.481.

Key Features

  • Authored by some of the foremost scientists in the field
  • Provides up-to-date information and directions for future research
  • Valuable reference material for advanced undergraduates, graduate students and professional scientists


Cell biologists, molecular biologists, developmental biologists, physiologists (organ level), biomedical scientists, biochemists studying cell-cell interactions, cell variation and evolution


No. of pages:
© Academic Press 2013
Academic Press
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About the Editors

Kwang Jeon Editor

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and Expertise

University of Tennessee, Knoxville, TN, USA