International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology

1st Edition - March 2, 2020

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  • Editor: Lorenzo Galluzzi
  • eBook ISBN: 9780128197462
  • Hardcover ISBN: 9780128197448

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International Review of Cell and Molecular Biology, Volume 350, covers all aspects of endoplasmic reticulum (ER) biology. With its multiple cellular functions, including ion storage as well protein folding, trafficking and secretion, the regulation of homeostasis within the ER is crucial to organismal health. New sections in this updated volume include DAMP emission upon ER stress, Protein misfolding disordersm Type I interferon response and ER stress, ER and autophagosome biogenesis, Mitochondria-associated membranes, ER calcium signaling in excitable cells, and ER in viral infections.

Key Features

  • Summarizes endoplasmic reticulum-related pathologies
  • Gives an update on the immunological aspects of ER-stress
  • Brings the links between ER homeostasis and autophagy


Cell biologists, Immunologists, Oncologists

Table of Contents

  • Preface: Endoplasmic reticulum in health and disease

    Lorenzo Galluzzi and Oliver Kepp

    1. Endoplasmic reticulum stress in the cellular release of damage-associated molecular patterns

    Alejandra Wu Chuang, Oliver Kepp, Guido Kroemer and Lucillia Bezu

    2. Emerging roles of the unfolded protein response (UPR) in the nervous system: A link with adaptive behavior to environmental stress?

    Mei-Li Díaz-Hung, Gabriela Martínez and Claudio Hetz

    3. Type I interferons and endoplasmic reticulum stress in health and disease

    Jenny Sprooten and Abhishek D. Garg

    4. The role of mitochondria-associated membranes in cellular homeostasis and diseases

    Mariasole Perrone, Natascia Caroccia, Ilaria Genovese, Sonia Missiroli, Lorenzo Modesti, Gaia Pedriali, Bianca Vezzani, Veronica Angela Maria Vitto, Michele Antenori, Magdalena Lebiedzinska-Arciszewska, Mariusz R. Wieckowski, Carlotta Giorgi and Paolo Pinton

    5. Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease

    Roberto Bravo-Sagua, Valentina Parra, Felipe Muñoz-Cordova, Pablo Sanchez-Aguilera, Valeria Garrido, Ariel Contreras-Ferrat, Mario Chiong and Sergio Lavandero

    6. Endoplasmic reticulum in viral infection

    Parikshit Bagchi

    7. Targeting endoplasmic reticulum stress and autophagy as therapeutic approaches for neurological diseases

    Annadurai Thangaraj, Susmita Sil, Ashutosh Tripathi, Ernest T. Chivero, Palsamy Periyasamy and Shilpa Buch

Product details

  • No. of pages: 344
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: March 2, 2020
  • Imprint: Academic Press
  • eBook ISBN: 9780128197462
  • Hardcover ISBN: 9780128197448

About the Serial Volume Editor

Lorenzo Galluzzi

Lorenzo Galluzzi
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.

Affiliations and Expertise

Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA

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