
International Review of Cell and Molecular Biology
Description
Key Features
- Includes comprehensive and detailed reviews on the current advances in cell and molecular biology
- Publishes only invited review articles on selected topics
- Authored by established and active cell and molecular biologists, drawn from international sources
- Offers a wide range of perspectives on specific subjects
Readership
The IRCMB series covers all fields of cell and molecular biology. IRCMB articles are addressed to a very wide public, ranging from undergraduate and graduate students to experienced scientists in a specific field
Table of Contents
Chapter One: New Insights Into the Roles of Retinoic Acid Signaling in Nervous System Development and the Establishment of Neurotransmitter Systems
- Abstract
- 1 Introduction
- 2 Developmental Signaling
- 3 Retinoids as Morphogens, Teratogens, and Drugs
- 4 RA Signaling Pathway
- 5 Major Functions of RA Signaling
- 6 RA Signaling During Nervous System Development
- 7 RA Signaling and the Establishment of Neurotransmitter Systems
- 8 RA Signaling Outside Vertebrates: Evolutionary Considerations
- 9 Concluding Remarks
- Acknowledgments
Chapter Two: AMBRA1, a Novel BH3-Like Protein: New Insights Into the AMBRA1–BCL2-Family Proteins Relationship
- Abstract
- 1 Introduction
- 2 AMBRA1 in Autophagy, Selective Autophagy, and Beyond
- 3 Autophagy and Apoptosis Cross-Talk
- 4 Autophagy Inhibition by the Oncogenic Function of BCL2
- 5 BCL2–AMBRA1 Interaction as a Novel Therapeutic Target
- 6 Conclusion
- Acknowledgments
Chapter Three: Rationale for the Combination of Dendritic Cell-Based Vaccination Approaches With Chemotherapy Agents
- Abstract
- 1 Introduction
- 2 Immunological Aspects of Anticancer Chemotherapy With Regards to DC Functions
- 3 Clinical Trials of Combined DC-Based Immunotherapy and Chemotherapy Affecting DC Functions
- 4 Conclusions
- Acknowledgments
Chapter Four: Smac Mimetics to Therapeutically Target IAP Proteins in Cancer
- Abstract
- 1 Introduction
- 2 IAP Proteins
- 3 Mechanisms of Action of Smac Mimetics
- 4 Smac Mimetics as Single Agents
- 5 Smac Mimetic-Based Combination Therapies
- 6 Conclusions
- Acknowledgments
Chapter Five: Consequences of Keratin Phosphorylation for Cytoskeletal Organization and Epithelial Functions
- Abstract
- 1 Introduction
- 2 Characteristics of Keratin Phosphorylation
- 3 Regulation of Protein Binding to Keratins by Phosphorylation
- 4 Role of Keratin Phosphorylation in Cell Physiology
- 5 Disease Relevance of Keratin Phosphorylation
- 6 Concluding Remarks: Significance of Keratin Phosphorylation
- Acknowledgments
Chapter Six: Plastid Protein Targeting: Preprotein Recognition and Translocation
- Abstract
- 1 Introduction
- 2 Origin of Plastids
- 3 Plastid Protein Targeting Routes
- 4 Regulation of Plastid Protein Import
- 5 Concluding Remarks
- Acknowledgments
Chapter Seven: Immunomodulatory Activity of VEGF in Cancer
- Abstract
- 1 Introduction
- 2 The VEGF Family
- 3 VEGF Receptors
- 4 The VEGF-A/VEGFR Axis
- 5 Antitumor Immunity
- 6 Immunosuppressive Roles of VEGF
- 7 Immunomodulatory Properties of Therapeutics Targeting VEGF
- 8 Medical Applications
- 9 Concluding Remarks
- Acknowledgments
Product details
- No. of pages: 352
- Language: English
- Copyright: © Academic Press 2017
- Published: February 17, 2017
- Imprint: Academic Press
- Hardcover ISBN: 9780128124673
- eBook ISBN: 9780128124680
About the Serial Editor
Lorenzo Galluzzi

Affiliations and Expertise
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