Intercellular Signaling in Development and Disease

1st Edition

Cell Signaling Collection

Authors:

  • Edward A. Dennis
  • Ralph Bradshaw
  • Intercellular Signaling in Development and Disease

    Print book

    Info/Buy

     In Stock

    Add to Cart

    Description

    Required reading for anyone involved in cell signaling research with articles written and edited by experts in the field. This title covers disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, andinflammatory bowel disease, along with up-to-date research on signaling systems and mutations in
    transcription factors that provide new targets for treating disease.

    Key Features

  • Articles written and edited by experts in the field
  • Thematic volume covering disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, and inflammatory bowel disease
  • Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease
  • Readership

    Professionals, researchers and graduate students in molecular biology, biochemistry, cell biology, biomedicine, structural biology, systems biology, and genetics.

    Details

    No. of pages:
    540
    Language:
    English
    Copyright:
    © 2011
    Published:
    Imprint:
    Academic Press
    Print ISBN:
    9780123822154
    Electronic ISBN:
    9780123822161

    About the authors

    Edward A. Dennis

    Edward A. Dennis is Distinguished Professor and former Chair of the Department of Chemistry and Biochemistry and Professor in the Department of Pharmacology in the School of Medicine at the University of California, San Diego. He is also Editor-in-Chief of the Journal of Lipid Research.

    Affiliations and Expertise

    Department of Chemistry and Biochemistry and Department of Pharmacology in the School of Medicine at the University of California, San Diego

    Ralph Bradshaw

    Ralph A. Bradshaw is Professor Emeritus in the Department of Physiology and biophysics at the University of California, Irvine. Prior to that he was on the faculty of the Department of Biological Chemistry, Washington University School of Medicine in St. Louis, MO and was Professor and Chair of the Department of Biological Chemistry at the University of California, Irvine. From 2006 to 2015, he was a member of the Mass Spectrometry Facility and Professor of Pharmaceutical Chemistry at the University of California, San Francisco. He holds degrees from Colby College and Duke University and was a post-doctoral fellow at Indiana University and the University of Washington. He has served as president for FASEB, was the founding president of the Protein Society and was the treasurer of the American Society for Biochemistry and Molecular Biology. His research has focused on protein chemistry and proteomics, with emphasis on the structure and function of growth factors and their receptors, particularly nerve growth factor and fibroblast growth factor, and the involvement of receptor tyrosine kinases in cell signalling. He has also studied in the role of proteolytic processing and N-terminal modification in protein stability and turnover.

    Affiliations and Expertise

    Department of Chemistry and Pharmaceutical Chemistry; and Mass Spectrometry Facility, University of California, San Francisco, Department of Physiology and Biophysics, College of Medicine, University of California, Irvine, Irvine, CA

    Reviews

    "The Cell Signaling Collection consists of four independent volumes which reprint articles from the second edition of the </Handbook of Cell Signaling/> carefully selected to alert medical and biological scientists to recent developments in the study of cellular signaling. This volume contains 57 articles exploring transduction mechanisms. After an overview of intracellular signaling, they cover phosporylation and dephosphorylation in kinases and phosphates, lipid signaling, cyclic nucleotides, and G proteins. The other volumes cover the functioning of transmembrane receptors, the regulation of organelle and cell compartment signaling, and intracellular signaling in development and disease."--Reference and Research Book News

    "For professionals, graduate researchers, and graduate students in biochemistry, biology, genetics, and biomedicine, Dennis (chemistry and biochemistry and pharmacology, U. of California, San Diego) and Bradshaw (chemistry and pharmaceutical chemistry, U. of California, San Francisco) bring together 52 articles from the authors' </Handbook of Cell Signaling/> on cell-cell signaling, signaling development, and signaling in disease. A group of biologists, chemists, oncologists, surgeons, and other scientists from the US, Europe, Singapore, and Australia emphasize the role of cell-cell interaction and organ and tissue effects in signaling activities and their disease implications. They do not cover other aspects of cell signaling like transmembrane receptor structure, receptor organization and function, intracellular signaling mechanisms, and transcriptional activation and responses in other organelles."--Reference and Research Book News