Insect Resistance Management

2nd Edition

Biology, Economics, and Prediction

Editors: David W. Onstad
Hardcover ISBN: 9780123969552
eBook ISBN: 9780123972330
Imprint: Academic Press
Published Date: 23rd October 2013
Page Count: 560
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Neither pest management nor resistance management can occur with only an understanding of pest biology. For years, entomologists have understood, with their use of economic thresholds, that at least a minimal use of economics was necessary for proper integrated pest management. IRM is even more complicated and dependent on understanding and using socioeconomic factors. The new edition of Insect Resistance Management addresses these issues and much more.

Many new ideas, facts and case studies have been developed since the previous edition of Insect Resistance Management published. With a new chapter focusing on Resistance Mechanisms Related to Plant-incorporated Toxins and heavily expanded revisions of several existing chapters, this new volume will be an invaluable resource for IRM researchers, practitioners, professors and advanced students. Authors in this edition include professors at major universities, leaders in the chemical and seed industry, evolutionary biologists and active IRM practitioners. This revision also contains more information about IRM outside North America, and a modeling chapter contains a large new section on uncertainty analysis, a subject recently emphasized by the U.S. Environmental Protection Agency. The final chapter contains a section on insecticidal seed treatments.

No other book has the breadth of coverage of Insect Resistance Management, 2e. It not only covers molecular to economic issues, but also transgenic crops, seed treatments and other pest management tactics such as crop rotation. Major themes continuing from the first edition include the importance of using IRM in the integrated pest management paradigm, the need to study and account for pest behavior, and the influence of human behavior and decision making in IRM.

Key Features

  • Provides insights from the history of insect resistance management (IRM) to the latest science
  • Includes contributions from experts on ecological aspects of IRM, molecular and population genetics, economics, and IRM social issues
  • Offers biochemistry and molecular genetics of insecticides presented with an emphasis on recent research
  • Encourages scientists and stakeholders to implement and coordinate strategies based on local social conditions


Pest control, crop science, agricultural economics researchers and scientists; entomologists; agricultural engineers; plant scientists; graduate-level students

Table of Contents


List of Contributors


Preface to Second Edition

Preface to the First Edition

Chapter 1. Major Issues in Insect Resistance Management

Philosophy and History

Major Themes



Chapter 2. Valuing Pest Susceptibility to Control

Goods and Values

Valuation of Pests

Discounting and Valuing the Future


Overview of Economic Models



Chapter 3. Understanding Resistance and Induced Responses of Insects to Xenobiotics and Insecticides in the Age of “Omics” and Systems Biology


General Mechanisms of Resistance

Resistance to Classes of Insecticides

Emerging Omics Technologies



Chapter 4. Plant Incorporated Protectants and Insect Resistance


Insecticidal Proteins

Mode of Action of Bt Proteins

RNA Interference

Resistance to Bt Proteins

PIP Dose and IRM



Chapter 5. Concepts and Complexities of Population Genetics

Without Natural Selection

Evolution Due to Natural Selection

Natural Selection in Patchy Landscapes

Gene Flow and Population Structure


Random Genetic Drift and Demographic Allee Effects

Genetic Architecture and Evolution

Selection Intensity and Genetics


Gene Interactions

Fitness Costs


Resistance Evolution and Pest Generation Time

Temporal and Spatial Scales in Hypotheses



Chapter 6. Resistance by Ectoparasites



Bed Bugs

Human Head Lice

Fleas of Cats and Dogs

Mites on Bees

Ticks of Cattle</


No. of pages:
© Academic Press 2014
Academic Press
eBook ISBN:
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About the Editor

David W. Onstad

Affiliations and Expertise

Insect Resistance Management Science, DuPont Agricultural Biotechnology, Wilmington, DE, USA


"...good editing has ensured a consistent writing style and prevented excess repetition. Also, the cross-referencing between the chapters helps tie them together. Nevertheless, the chapters stand very well on their own…a very readable prose."--Bulletin of the ESC, Insect Resistance Management, Second Edition

“This updated edition…is an excellent overview of IRM; hopefully, future researchers will work closely with plant pathologists, plant breeders, and even medical scientists struggling with very similar issues plaguing society that appear to stem from very similar biological processes. Summing Up: Highly recommended.”--CHOICE, July 2014

"…recent advances in this dynamic field are well documented and explained in the second edition of the book…easy to read and the language is very accessible to non-specialists, so it should be considered a very valuable reference for students and professional researchers interested in IRM, including insect pathologists involved in the use of entomopathogens for pest control."--Society for Invertebrate Pathology Newsletter, June 2014
"Contributors from entomology, agriculture, and economics explore aspects of managing insect resistance to pesticides, reporting their own results, reviewing those of others, and offering practical suggestions for applying them. Among the topics are understanding resistance and induced responses of insects to xenobiotics and insecticides in the age of "omics" and systems biology, concepts and complexities of population genetics,…"--, February 2014